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Samuel G Rodriques

Explore the profile of Samuel G Rodriques including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 1028
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Recent Articles
1.
Rodriques S
Cell . 2024 Jan; 187(1):3-7. PMID: 38181742
Academia is a vital source of innovation and discovery, but it faces challenges in funding and coordination. These challenges limit the scope and impact of academic research. Now, philanthropists and...
2.
Jablonka K, Ai Q, Al-Feghali A, Badhwar S, Bocarsly J, M Bran A, et al.
Digit Discov . 2023 Nov; 2(5):1233-1250. PMID: 38013906
Large-language models (LLMs) such as GPT-4 caught the interest of many scientists. Recent studies suggested that these models could be useful in chemistry and materials science. To explore these possibilities,...
3.
Marblestone A, Gamick A, Kalil T, Martin C, Cvitkovic M, Rodriques S
Nature . 2022 Jan; 601(7892):188-190. PMID: 35017702
No abstract available.
4.
Marshall J, Doughty B, Subramanian V, Guckelberger P, Wang Q, Chen L, et al.
Proc Natl Acad Sci U S A . 2020 Dec; 117(52):33404-33413. PMID: 33376219
Single-cell quantification of RNAs is important for understanding cellular heterogeneity and gene regulation, yet current approaches suffer from low sensitivity for individual transcripts, limiting their utility for many applications. Here...
5.
Rodriques S, Chen L, Liu S, Zhong E, Scherrer J, Boyden E, et al.
Nat Biotechnol . 2020 Oct; 39(3):320-325. PMID: 33077959
Current approaches to single-cell RNA sequencing (RNA-seq) provide only limited information about the dynamics of gene expression. Here we present RNA timestamps, a method for inferring the age of individual...
6.
Rodriques S, Stickels R, Goeva A, Martin C, Murray E, Vanderburg C, et al.
Science . 2019 Mar; 363(6434):1463-1467. PMID: 30923225
Spatial positions of cells in tissues strongly influence function, yet a high-throughput, genome-wide readout of gene expression with cellular resolution is lacking. We developed Slide-seq, a method for transferring RNA...
7.
Rodriques S, Marblestone A, Boyden E
PLoS One . 2019 Mar; 14(3):e0212868. PMID: 30921350
We propose and theoretically study an approach to massively parallel single molecule peptide sequencing, based on single molecule measurement of the kinetics of probe binding (Havranek, et al., 2013) to...
8.
Oran D, Rodriques S, Gao R, Asano S, Skylar-Scott M, Chen F, et al.
Science . 2018 Dec; 362(6420):1281-1285. PMID: 30545883
Lithographic nanofabrication is often limited to successive fabrication of two-dimensional (2D) layers. We present a strategy for the direct assembly of 3D nanomaterials consisting of metals, semiconductors, and biomolecules arranged...
9.
Rodriques S, Marblestone A, Scholvin J, Dapello J, Sarkar D, Mankin M, et al.
J Biomed Opt . 2016 May; 21(5):57003. PMID: 27194640
We introduce the design and theoretical analysis of a fiber-optic architecture for neural recording without contrast agents, which transduces neural electrical signals into a multiplexed optical readout. Our sensor design...