Douglas G Stewart
Overview
Explore the profile of Douglas G Stewart including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
592
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0
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Recent Articles
1.
Lytras S, Wickenhagen A, Sugrue E, Stewart D, Swingler S, Sims A, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002398.
PMID: 38015855
The prenylated form of the human 2'-5'-oligoadenylate synthetase 1 (OAS1) protein has been shown to potently inhibit the replication of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus responsible...
2.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull M, et al.
Science
. 2021 Sep;
374(6567):eabj3624.
PMID: 34581622
Inherited genetic factors can influence the severity of COVID-19, but the molecular explanation underpinning a genetic association is often unclear. Intracellular antiviral defenses can inhibit the replication of viruses and...
3.
Shaw A, Rihn S, Mollentze N, Wickenhagen A, Stewart D, Orton R, et al.
PLoS Biol
. 2021 Sep;
19(9):e3001352.
PMID: 34491982
Antiviral defenses can sense viral RNAs and mediate their destruction. This presents a challenge for host cells since they must destroy viral RNAs while sparing the host mRNAs that encode...
4.
Rihn S, Merits A, Bakshi S, Turnbull M, Wickenhagen A, Alexander A, et al.
PLoS Biol
. 2021 Feb;
19(2):e3001091.
PMID: 33630831
The recent emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the underlying cause of Coronavirus Disease 2019 (COVID-19), has led to a worldwide pandemic causing substantial morbidity, mortality, and...
5.
Banerjee A, Blanco M, Bruce E, Honson D, Chen L, Chow A, et al.
Cell
. 2020 Oct;
183(5):1325-1339.e21.
PMID: 33080218
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently identified coronavirus that causes the respiratory disease known as coronavirus disease 2019 (COVID-19). Despite the urgent need, we still do...
6.
Rihn S, Aziz M, Stewart D, Hughes J, Turnbull M, Varela M, et al.
J Virol
. 2019 Aug;
93(20).
PMID: 31375575
Vesicular stomatitis Indiana virus (VSIV), formerly known as vesicular stomatitis virus (VSV) Indiana (VSV), is a model virus that is exceptionally sensitive to the inhibitory action of interferons (IFNs). Interferons...