Lilia Magomedova
Overview
Explore the profile of Lilia Magomedova including associated specialties, affiliations and a list of published articles.
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29
Citations
553
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Recent Articles
1.
Sahin C, Melanson J, Le Billan F, Magomedova L, Ferreira T, Oliveira A, et al.
Mol Metab
. 2024 May;
85:101958.
PMID: 38763495
Objective: The prevalence of metabolic diseases is increasing globally at an alarming rate; thus, it is essential that effective, accessible, low-cost therapeutics are developed. Peroxisome proliferator-activated receptors (PPARs) are transcription...
2.
Kamal M, Tokmakjian L, Knox J, Han D, Moshiri H, Magomedova L, et al.
PLoS Genet
. 2023 Nov;
19(11):e1011008.
PMID: 37930961
The cuticles of ecdysozoan animals are barriers to material loss and xenobiotic insult. Key to this barrier is lipid content, the establishment of which is poorly understood. Here, we show...
3.
Kantor S, Lanigan M, Giggins L, Lione L, Magomedova L, de Lannoy I, et al.
Behav Brain Res
. 2023 May;
449:114473.
PMID: 37146722
Wistar-Kyoto (WKY) rats exhibit depression-like characteristics and decreased sensitivity to monoamine-based antidepressants, making them a suitable model of treatment-resistant depression (TRD). Ketamine has emerged recently as a rapidly acting antidepressant...
4.
Liu J, Sahin C, Ahmad S, Magomedova L, Zhang M, Jia Z, et al.
Sci Signal
. 2022 Jul;
15(741):eabo1857.
PMID: 35857636
The nuclear receptor peroxisome proliferator-activated receptor alpha (PPARα) is emerging as an important target in the brain for the treatment or prevention of cognitive disorders. The identification of high-affinity ligands...
5.
Sahin C, Magomedova L, Ferreira T, Liu J, Tiefenbach J, Alves P, et al.
J Med Chem
. 2022 Jan;
65(3):1961-1978.
PMID: 35089724
Metabolic diseases are increasing at staggering rates globally. The peroxisome proliferator-activated receptors (PPARα/γ/δ) are fatty acid sensors that help mitigate imbalances between energy uptake and utilization. Herein, we report compounds...
6.
Higgins G, Carroll N, Brown M, MacMillan C, Silenieks L, Thevarkunnel S, et al.
Front Pharmacol
. 2021 Mar;
12:640241.
PMID: 33716753
Long term benefits following short-term administration of high psychedelic doses of serotonergic and dissociative hallucinogens, typified by psilocybin and ketamine respectively, support their potential as treatments for psychiatric conditions such...
7.
Kamal M, Moshiri H, Magomedova L, Han D, Nguyen K, Yeo M, et al.
Nat Commun
. 2019 Sep;
10(1):3938.
PMID: 31477732
The nematode Caenorhabditis elegans is a bacterivore filter feeder. Through the contraction of the worm's pharynx, a bacterial suspension is sucked into the pharynx's lumen. Excess liquid is then shunted...
8.
Magomedova L, Cummins C
Methods Mol Biol
. 2019 Mar;
1951:1-14.
PMID: 30825140
Oxidative derivatives of cholesterol such as 22(R)-hydroxycholesterol, 24(S)-hydroxycholesterol, 25-hydroxycholesterol, and (25S),26-hydroxycholesterol are endogenous ligands for the liver X receptors (LXRα and LXRβ). The LXRs are nuclear hormone receptors known as...
9.
Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, et al.
Nucleic Acids Res
. 2019 Jan;
47(6):2856-2870.
PMID: 30698747
Stress hormones bind and activate the glucocorticoid receptor (GR) in many tissues including the brain. We identified arginine and glutamate rich 1 (ARGLU1) in a screen for new modulators of...
10.
Tiefenbach J, Magomedova L, Liu J, Reunov A, Tsai R, Eappen N, et al.
Dis Model Mech
. 2018 Sep;
11(9).
PMID: 30171034
Current peroxisome proliferator-activated receptor (PPAR)-targeted drugs, such as the PPARγ-directed diabetes drug rosiglitazone, are associated with undesirable side effects due to robust agonist activity in non-target tissues. To find new...