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Liesbet Temmerman

Explore the profile of Liesbet Temmerman including associated specialties, affiliations and a list of published articles. Areas
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Articles 55
Citations 1122
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Recent Articles
1.
Maetens L, Maiti B, Cools F, Verheye S, Daelemans D, Persoons L, et al.
Bioorg Med Chem . 2025 Feb; 121:118115. PMID: 40010036
To evaluate the effect of amination on biofilm inhibition against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus, representative compounds of two previously described 5-aryl-2-aminoimidazole (5-Ar-2-AI) classes were aminated by installing...
2.
McCoy C, Wray C, Freeman L, Crooks B, Golinelli L, Marks N, et al.
BMC Genomics . 2024 Dec; 25(1):1220. PMID: 39702046
Background: Parasitic nematodes significantly undermine global human and animal health and productivity. Parasite control is reliant on anthelmintic administration however over-use of a limited number of drugs has resulted in...
3.
Golinelli L, Geens E, Irvine A, McCoy C, Vandewyer E, Atkinson L, et al.
BMC Biol . 2024 Oct; 22(1):223. PMID: 39379997
Background: The phylum Nematoda is incredibly diverse and includes many parasites of humans, livestock, and plants. Peptide-activated G protein-coupled receptors (GPCRs) are central to the regulation of physiology and numerous...
4.
Driesschaert B, Mergan L, Lucci C, Simon C, Santos D, De Groef L, et al.
Biogerontology . 2024 Aug; 25(6):1301-1314. PMID: 39168928
While the main role of phagocytic scavenger cells consists of the neutralization and elimination of pathogens, they also keep the body fluids clean by taking up and breaking down waste...
5.
Thiel D, Alfonso Yanez Guerra L, Kieswetter A, Cole A, Temmerman L, Technau U, et al.
Elife . 2024 May; 12. PMID: 38727714
Neuropeptides are ancient signaling molecules in animals but only few peptide receptors are known outside bilaterians. Cnidarians possess a large number of G protein-coupled receptors (GPCRs) - the most common...
6.
Van Bael S, Ludwig C, Baggerman G, Temmerman L
Methods Mol Biol . 2024 Mar; 2758:341-373. PMID: 38549024
The nematode Caenorhabditis elegans lends itself as an excellent model organism for peptidomics studies. Its ease of cultivation and quick generation time make it suitable for high-throughput studies. The nervous...
7.
Parmar B, Kieswetter A, Geens E, Vandewyer E, Ludwig C, Temmerman L
PLoS Biol . 2023 Sep; 21(9):e3002300. PMID: 37713439
Overlapping genes are widely prevalent; however, their expression and consequences are poorly understood. Here, we describe and functionally characterize a novel zyx-1 overlapping gene, azyx-1, with distinct regulatory functions in...
8.
McClanahan P, Golinelli L, Le T, Temmerman L
PLoS One . 2023 Aug; 18(8):e0289326. PMID: 37527261
Entomopathogenic nematodes, including Steinernema spp., play an increasingly important role as biological alternatives to chemical pesticides. The infective juveniles of these worms use nictation-a behavior in which animals stand on...
9.
Mergan L, Driesschaert B, Temmerman L
PLoS One . 2023 Jun; 18(6):e0287933. PMID: 37368903
A rather peculiar but very potent means of achieving longevity is through axenic dietary restriction (ADR), where animals feed on (semi-)defined culture medium in absence of any other lifeform. The...
10.
McClanahan P, Le T, Cockx B, Temmerman L
MicroPubl Biol . 2023 May; 2023. PMID: 37179972
Cryopreservation allows strains to be stored, eliminating genetic drift and maintenance costs. Existing cryopreservation methods for the economically-important entomopathogenic nematode involve multiple incubation and filtration steps to precondition the animals....