Isabel Beets
Overview
Explore the profile of Isabel Beets including associated specialties, affiliations and a list of published articles.
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Articles
65
Citations
1057
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Recent Articles
1.
Chen L, Beets I, Schafer W
MicroPubl Biol
. 2025 Feb;
2025.
PMID: 39936042
Two-pore domain potassium channels, also known as K2P channels, play vital roles in maintaining the resting membrane potential in excitable cells, affecting a variety of physiological processes across species. The...
2.
McCoy C, Wray C, Freeman L, Crooks B, Golinelli L, Marks N, et al.
BMC Genomics
. 2024 Dec;
25(1):1220.
PMID: 39702046
Background: Parasitic nematodes significantly undermine global human and animal health and productivity. Parasite control is reliant on anthelmintic administration however over-use of a limited number of drugs has resulted in...
3.
Toker I, Ripoll-Sanchez L, Geiger L, Saini K, Beets I, Vertes P, et al.
bioRxiv
. 2024 Dec;
PMID: 39651161
One avenue to better understand brain evolution is to map molecular patterns of evolutionary changes in neuronal cell types across entire nervous systems of distantly related species. Generating whole-animal single-cell...
4.
Buckley M, Jacob W, Bortey L, McClain M, Ritter A, Godfrey A, et al.
PLoS Genet
. 2024 Nov;
20(11):e1011461.
PMID: 39561202
Modulation of neurotransmission is key for organismal responses to varying physiological contexts such as during infection, injury, or other stresses, as well as in learning and memory and for sensory...
5.
Hierarchical regulation of functionally antagonistic neuropeptides expressed in a single neuron pair
Aoki I, Golinelli L, Dunkel E, Bhat S, Bassam E, Beets I, et al.
Nat Commun
. 2024 Nov;
15(1):9504.
PMID: 39489735
Neuronal communication involves small-molecule transmitters, gap junctions, and neuropeptides. While neurons often express multiple neuropeptides, our understanding of the coordination of their actions and their mutual interactions remains limited. Here,...
6.
Butt A, Van Damme S, Santiago E, Olson A, Beets I, Koelle M
Curr Biol
. 2024 Oct;
34(20):4704-4714.e5.
PMID: 39395419
Neurons typically release both a neurotransmitter and one or more neuropeptides, but how these signals are integrated within neural circuits to generate and tune behaviors remains poorly understood. We studied...
7.
Golinelli L, Geens E, Irvine A, McCoy C, Vandewyer E, Atkinson L, et al.
BMC Biol
. 2024 Oct;
22(1):223.
PMID: 39379997
Background: The phylum Nematoda is incredibly diverse and includes many parasites of humans, livestock, and plants. Peptide-activated G protein-coupled receptors (GPCRs) are central to the regulation of physiology and numerous...
8.
Watteyne J, Chudinova A, Ripoll-Sanchez L, Schafer W, Beets I
Genetics
. 2024 Sep;
228(3).
PMID: 39344922
Neuropeptides are abundant signaling molecules that control neuronal activity and behavior in all animals. Owing in part to its well-defined and compact nervous system, Caenorhabditis elegans has been one of...
9.
Hafker N, Holcik L, Mat A, Coric A, Vadiwala K, Beets I, et al.
PLoS Biol
. 2024 Apr;
22(4):e3002572.
PMID: 38603542
The circadian clock controls behavior and metabolism in various organisms. However, the exact timing and strength of rhythmic phenotypes can vary significantly between individuals of the same species. This is...
10.
Marquina-Solis J, Feng L, Vandewyer E, Beets I, Hawk J, Colon-Ramos D, et al.
Cell Rep
. 2024 Apr;
43(4):114042.
PMID: 38573858
Pathogenic infection elicits behaviors that promote recovery and survival of the host. After exposure to the pathogenic bacterium Pseudomonas aeruginosa PA14, the nematode Caenorhabditis elegans modifies its sensory preferences to...