Lia Lewis-Ximenez
Overview
Explore the profile of Lia Lewis-Ximenez including associated specialties, affiliations and a list of published articles.
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10
Citations
469
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Recent Articles
1.
Flores G, Lago B, Caetano A, Silva J, Marques V, Brandao-Mello C, et al.
Braz J Infect Dis
. 2025 Feb;
29(2):104512.
PMID: 39985934
Background: Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) share the same routes of transmission, therefore, co-infection by both viruses represents a challenge to the goal of eliminating viral hepatitis...
2.
Chen D, Wolski D, Aneja J, Matsubara L, Robilotti B, Hauck G, et al.
J Clin Invest
. 2020 Jan;
130(2):768-773.
PMID: 31904582
CD4+ T cell failure is a hallmark of chronic hepatitis C virus (HCV) infection. However, the mechanisms underlying the impairment and loss of virus-specific CD4+ T cells in persisting HCV...
3.
Yu W, Cosgrove C, Berger C, Cheney P, Krykbaeva M, Kim A, et al.
Pathog Immun
. 2018 Mar;
3(1):2-18.
PMID: 29541698
Background: Hepatitis B virus (HBV) affects up to 400 million people worldwide and accounts for approximately one million deaths per year from liver pathologies. Current treatment regimens are effective in...
4.
Lampe E, Lewis-Ximenez L, Espirito-Santo M, Delvaux N, Pereira S, Peres-da-Silva A, et al.
Antivir Ther
. 2013 Jun;
18(3 Pt B):435-44.
PMID: 23792792
Background: Many studies have documented the molecular epidemiological scenario of HCV within individual Brazilian states, but we still have an incomplete understanding of the dispersion dynamics of the virus in...
5.
Ramos J, Silva R, Hoffmann L, Ramos A, Cabello P, Urmenyi T, et al.
BMC Res Notes
. 2012 Sep;
5:508.
PMID: 22986179
Background: Cytokines play an important role in the regulation of the immune response. In hepatitis C virus (HCV) infection, cytokine levels may influence the outcome of acute HCV infection. Polymorphisms...
6.
Schulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan B, Streeck H, et al.
J Exp Med
. 2012 Jan;
209(1):61-75.
PMID: 22213804
Vigorous proliferative CD4(+) T cell responses are the hallmark of spontaneous clearance of acute hepatitis C virus (HCV) infection, whereas comparable responses are absent in chronically evolving infection. Here, we...
7.
Kasprowicz V, Kang Y, Lucas M, Schulze Zur Wiesch J, Kuntzen T, Fleming V, et al.
J Virol
. 2009 Nov;
84(3):1656-63.
PMID: 19906915
Hepatitis C virus (HCV)-specific CD8(+) T cells in persistent HCV infection are low in frequency and paradoxically show a phenotype associated with controlled infections, expressing the memory marker CD127. We...
8.
Kasprowicz V, Ward S, Turner A, Grammatikos A, Nolan B, Lewis-Ximenez L, et al.
J Clin Invest
. 2008 Feb;
118(3):1143-53.
PMID: 18246203
Cross-reactivity of murine and recently human CD8(+) T cells between different viral peptides, i.e., heterologous immunity, has been well characterized. However, the directionality and quality of these cross-reactions is critical...
9.
Kasprowicz V, Schulze Zur Wiesch J, Kuntzen T, Nolan B, Longworth S, Berical A, et al.
J Virol
. 2007 Dec;
82(6):3154-60.
PMID: 18160439
We monitored expression of PD-1 (a mediator of T-cell exhaustion and viral persistence) on hepatitis C virus (HCV)-specific CD8(+) and CD4(+) T cells from blood and liver during acute and...
10.
Schulze Zur Wiesch J, Lauer G, Day C, Kim A, Ouchi K, Duncan J, et al.
J Immunol
. 2005 Sep;
175(6):3603-13.
PMID: 16148104
A vigorous hepatitis C virus (HCV)-specific Th cell response is regarded as essential to the immunological control of HCV viremia. The aim of this study was to comprehensively define the...