Leonore Wigger
Overview
Explore the profile of Leonore Wigger including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
400
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0
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Recent Articles
1.
Mehl F, Sanchez-Archidona A, Meitil I, Gerl M, Cruciani-Guglielmacci C, Wigger L, et al.
iScience
. 2024 Nov;
27(11):111134.
PMID: 39507247
To identify the pathways that are coordinately regulated in pancreatic β cells, muscle, liver, and fat to control fasting glycemia we fed C57Bl/6, DBA/2, and Balb/c mice a regular chow...
2.
Kompotis K, Mang G, Hubbard J, Jimenez S, Emmenegger Y, Polysopoulos C, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(3):e2220532121.
PMID: 38207077
MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression that have been implicated in a plethora of neuronal processes. Nevertheless, their role in regulating brain activity in the context of...
3.
Aghagolzadeh P, Plaisance I, Bernasconi R, Treibel T, Pulido Quetglas C, Wyss T, et al.
Circulation
. 2023 Jul;
148(9):778-797.
PMID: 37427428
Background: Cardiac fibroblasts have crucial roles in the heart. In particular, fibroblasts differentiate into myofibroblasts in the damaged myocardium, contributing to scar formation and interstitial fibrosis. Fibrosis is associated with...
4.
Bignon Y, Wigger L, Ansermet C, Weger B, Lagarrigue S, Centeno G, et al.
J Clin Invest
. 2023 Mar;
133(8).
PMID: 36862511
Circadian rhythmicity in renal function suggests rhythmic adaptations in renal metabolism. To decipher the role of the circadian clock in renal metabolism, we studied diurnal changes in renal metabolic pathways...
5.
Ince Y, Krahmer J, Fiorucci A, Trevisan M, Galvao V, Wigger L, et al.
Nat Commun
. 2022 Oct;
13(1):5659.
PMID: 36216814
Plant growth ultimately depends on fixed carbon, thus the available light for photosynthesis. Due to canopy light absorption properties, vegetative shade combines low blue (LB) light and a low red...
6.
Sanchez-Archidona A, Cruciani-Guglielmacci C, Roujeau C, Wigger L, Lallement J, Denom J, et al.
Mol Metab
. 2021 Oct;
54:101355.
PMID: 34634522
Objectives: To find plasma biomarkers prognostic of type 2 diabetes, which could also inform on pancreatic β-cell deregulations or defects in the function of insulin target tissues. Methods: We conducted...
7.
Wigger L, Barovic M, Brunner A, Marzetta F, Schoniger E, Mehl F, et al.
Nat Metab
. 2021 Jun;
3(7):1017-1031.
PMID: 34183850
Most research on human pancreatic islets is conducted on samples obtained from normoglycaemic or diseased brain-dead donors and thus cannot accurately describe the molecular changes of pancreatic islet beta cells...
8.
Fontana P, Ibberson M, Stevenson B, Wigger L, Daali Y, Niknejad A, et al.
J Thromb Haemost
. 2020 Feb;
18(6):1425-1434.
PMID: 32077582
Background: On-clopidogrel platelet reactivity (PR) is associated with the risk of thrombotic or bleeding event in selected populations of high-risk patients. PR is a highly heritable phenotype and a few...
9.
Thorens B, Rodriguez A, Cruciani-Guglielmacci C, Wigger L, Ibberson M, Magnan C
Mol Metab
. 2019 Sep;
27S:S147-S154.
PMID: 31500826
Background: Progression from pre-diabetes to type 2 diabetes (T2D) and from T2D to insulin requirement proceeds at very heterogenous rates among patient populations, and the risk of developing different types...
10.
Wigger L, Casals-Casas C, Baruchet M, Trang K, Pradervand S, Naldi A, et al.
PLoS One
. 2019 Aug;
14(8):e0220894.
PMID: 31437187
Transcriptional regulations exert a critical control of metabolic homeostasis. In particular, the nuclear receptors (NRs) are involved in regulating numerous pathways of the intermediate metabolism. The purpose of the present...