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Bernard Thorens

Explore the profile of Bernard Thorens including associated specialties, affiliations and a list of published articles. Areas
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Articles 165
Citations 8489
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Recent Articles
1.
Fu H, Vuononvirta J, Fanti S, Bonacina F, dAmati A, Wang G, et al.
Nat Metab . 2025 Feb; PMID: 40000839
No abstract available.
2.
Tutas J, Tolve M, Ozer-Yildiz E, Ickert L, Klein I, Silverman Q, et al.
Nat Metab . 2025 Jan; 7(2):297-320. PMID: 39815080
Dysfunctions in autophagy, a cellular mechanism for breaking down components within lysosomes, often lead to neurodegeneration. The specific mechanisms underlying neuronal vulnerability due to autophagy dysfunction remain elusive. Here we...
3.
Mehl F, Sanchez-Archidona A, Meitil I, Gerl M, Cruciani-Guglielmacci C, Wigger L, et al.
iScience . 2024 Nov; 27(11):111134. PMID: 39507247
To identify the pathways that are coordinately regulated in pancreatic β cells, muscle, liver, and fat to control fasting glycemia we fed C57Bl/6, DBA/2, and Balb/c mice a regular chow...
4.
Brunner M, Lopez-Rodriguez D, Estrada-Meza J, Dali R, Rohrbach A, Deglise T, et al.
Nat Commun . 2024 Aug; 15(1):6604. PMID: 39098920
The ependyma lining the third ventricle (3V) in the mediobasal hypothalamus plays a crucial role in energy balance and glucose homeostasis. It is characterized by a high functional heterogeneity and...
5.
Thorens B, Hodson D
Diabetes . 2024 Jun; 73(7):1027-1031. PMID: 38900951
The glucagon-like peptide-1 receptor (GLP-1R) is a class B G protein-coupled receptor involved in the regulation of blood glucose levels and food intake. Stabilized agonists targeting GLP-1R are used in...
6.
McNeilly A, Gallagher J, Evans M, de Galan B, Pedersen-Bjergaard U, Thorens B, et al.
Diabetologia . 2024 Jun; 67(8):1724. PMID: 38864888
No abstract available.
7.
Vickneson K, Blackburn J, Gallagher J, Evans M, de Galan B, Pedersen-Bjergaard U, et al.
Diabetologia . 2024 Jun; 67(8):1723. PMID: 38825626
No abstract available.
8.
Thorens B
Physiol Rev . 2024 Apr; 104(4):1461-1486. PMID: 38661565
Glucose homeostasis is mainly under the control of the pancreatic islet hormones insulin and glucagon, which, respectively, stimulate glucose uptake and utilization by liver, fat, and muscle and glucose production...
9.
Castillo-Armengol J, Marzetta F, Sanchez-Archidona A, Fledelius C, Evans M, McNeilly A, et al.
Diabetologia . 2024 Jan; 67(2):403. PMID: 38206364
No abstract available.
10.
Gandasi N, Gao R, Kothegala L, Pearce A, Santos C, Acreman S, et al.
Diabetologia . 2023 Dec; 67(3):528-546. PMID: 38127123
Aims/hypothesis: Diabetes mellitus is associated with impaired insulin secretion, often aggravated by oversecretion of glucagon. Therapeutic interventions should ideally correct both defects. Glucagon-like peptide 1 (GLP-1) has this capability but...