Ioannis Xenarios
Overview
Explore the profile of Ioannis Xenarios including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Articles
183
Citations
13517
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Recent Articles
1.
Ducrest A, San-Jose L, Neuenschwander S, Schmid-Siegert E, Simon C, Pagni M, et al.
Pigment Cell Melanoma Res
. 2025 Feb;
38(2):e70001.
PMID: 39910963
Regulation of melanin-based pigmentation is complex, involving multiple genes. Because different genes can contribute to the same pigmentation phenotype, the genes identified in model organisms may not necessarily apply to...
2.
Bachmann Salvy M, Santuari L, Schmid-Siegert E, Lykoskoufis N, Xenarios I, Arpat B
MAbs
. 2024 Oct;
16(1):2408344.
PMID: 39379324
Antibodies have emerged as the leading class of biotherapeutics, yet traditional screening methods face significant time and resource challenges in identifying lead candidates. Integrating high-throughput sequencing with computational approaches marks...
3.
Wertenbroek R, Hofmeister R, Xenarios I, Thoma Y, Delaneau O
PLoS Genet
. 2024 Jul;
20(7):e1011092.
PMID: 38959269
Haplotype estimation, or phasing, has gained significant traction in large-scale projects due to its valuable contributions to population genetics, variant analysis, and the creation of reference panels for imputation and...
4.
Schmid-Siegert E, Qin M, Tian H, Arpat B, Chen B, Xenarios I
G3 (Bethesda)
. 2023 Aug;
13(10).
PMID: 37594081
Mouse xenograft models play a vital role in tumor studies for research as well as for screening of drugs for the pharmaceutical industry. In particular, models with compromised immunity are...
5.
Wertenbroek R, Xenarios I, Thoma Y, Delaneau O
Bioinform Adv
. 2023 Mar;
3(1):vbad021.
PMID: 36908398
Summary: The positional Burrows-Wheeler transform (PBWT) data structure allows for efficient haplotype data matching and compression. Its performance makes it a powerful tool for bioinformatics. However, existing algorithms do not...
6.
Forny P, Bonilla X, Lamparter D, Shao W, Plessl T, Frei C, et al.
Nat Metab
. 2023 Jan;
5(1):80-95.
PMID: 36717752
Methylmalonic aciduria (MMA) is an inborn error of metabolism with multiple monogenic causes and a poorly understood pathogenesis, leading to the absence of effective causal treatments. Here we employ multi-layered...
7.
Emmenegger M, De Cecco E, Lamparter D, Jacquat R, Riou J, Menges D, et al.
iScience
. 2023 Jan;
26(2):105928.
PMID: 36619367
Effective public health measures against SARS-CoV-2 require granular knowledge of population-level immune responses. We developed a Tripartite Automated Blood Immunoassay (TRABI) to assess the IgG response against three SARS-CoV-2 proteins....
8.
Taylor A, Barros D, Gobet N, Schuepbach T, McAllister B, Aeschbach L, et al.
NAR Genom Bioinform
. 2022 Dec;
4(4):lqac089.
PMID: 36478959
Targeted DNA sequencing approaches will improve how the size of short tandem repeats is measured for diagnostic tests and preclinical studies. The expansion of these sequences causes dozens of disorders,...
9.
Medaglia C, Kolpakov I, Zwygart A, Zhu Y, Constant S, Huang S, et al.
Commun Biol
. 2022 Oct;
5(1):1075.
PMID: 36216966
Influenza makes millions of people ill every year, placing a large burden on the healthcare system and the economy. To develop a treatment against influenza, we combined virucidal sialylated cyclodextrins...
10.
Gobet N, Jan M, Franken P, Xenarios I
PLoS Comput Biol
. 2022 Sep;
18(9):e1010552.
PMID: 36155976
Genetic variations affect behavior and cause disease but understanding how these variants drive complex traits is still an open question. A common approach is to link the genetic variants to...