Leonidas Tsiokas
Overview
Explore the profile of Leonidas Tsiokas including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1400
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0
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Recent Articles
1.
Elechalawar C, Rao G, Gulla S, Patel M, Frickenstein A, Means N, et al.
ACS Nano
. 2024 Mar;
18(12):9242.
PMID: 38465974
No abstract available.
2.
Patel M, Gerakopoulos V, Petsouki E, Zimmerman K, Tsiokas L
bioRxiv
. 2024 Mar;
PMID: 38464230
Nephronophthisis (NPHP) and autosomal dominant Polycystic Kidney Disease (ADPKD) are two genetically distinct forms of Polycystic Kidney Disease (PKD), yet both diseases present with kidney cysts and a gradual decline...
3.
Houser J, Patel M, Wright K, Onopiuk M, Tsiokas L, Humphrey M
Blood Cells Mol Dis
. 2023 Jun;
102:102760.
PMID: 37267696
Hematopoiesis and lineage commitment are regulated by several conserved cell-intrinsic signaling pathways, including MAPKs and β-catenin/TCF/LEF. The Inhibitor of MyoD Family A (I-MFA), a transcriptional repressor and tumor suppressor gene,...
4.
Elechalawar C, Rao G, Gulla S, Patel M, Frickenstein A, Means N, et al.
ACS Nano
. 2023 May;
17(10):9326-9337.
PMID: 37129853
The RAS-transformed cells utilize macropinocytosis to acquire amino acids to support their uncontrolled growth. However, targeting RAS to inhibit macropinocytosis remains a challenge. Here, we report that gold nanoparticles (GNP)...
5.
Patel M, Tsiokas L
Cells
. 2021 Nov;
10(11).
PMID: 34831200
The primary cilium, an antenna-like structure that protrudes out from the cell surface, is present in most cell types. It is a microtubule-based organelle that serves as a mega-signaling center...
6.
Petsouki E, Gerakopoulos V, Szeto N, Chang W, Humphrey M, Tsiokas L
Commun Biol
. 2021 Sep;
4(1):1066.
PMID: 34518642
Structural defects in primary cilia have robust effects in diverse tissues and systems. However, how disorders of ciliary length lead to functional outcomes are unknown. We examined the functional role...
7.
Gerakopoulos V, Ngo P, Tsiokas L
Life Sci Alliance
. 2020 Jul;
3(9).
PMID: 32651191
The primary cilium is a microtubule-based, antenna-like organelle housing several signaling pathways. It follows a cyclic pattern of assembly and deciliation (disassembly and/or shedding), as cells exit and re-enter the...
8.
Hardy E, Tsiokas L
Cell Signal
. 2020 Apr;
72:109640.
PMID: 32305669
Naturally occurring mutations in two separate genes, PKD1 and PKD2, are responsible for the vast majority of all cases of autosomal dominant polycystic kidney disease (ADPKD), one of the most...
9.
Onopiuk M, Eby B, Nesin V, Ngo P, Lerner M, Gorvin C, et al.
JCI Insight
. 2020 Mar;
5(8).
PMID: 32213715
Familial hypocalciuric hypercalcemia (FHH) is a genetic condition associated with hypocalciuria, hypercalcemia, and, in some cases, inappropriately high levels of circulating parathyroid hormone (PTH). FHH is associated with inactivating mutations...
10.
Yazdizadeh Shotorbani P, Chaudhari S, Tao Y, Tsiokas L, Ma R
Am J Physiol Renal Physiol
. 2020 Jan;
318(3):F673-F682.
PMID: 31984795
Overproduction of extracellular matrix proteins, including fibronectin by mesangial cells (MCs), contributes to diabetic nephropathy. Inhibitor of myogenic differentiation family isoform a (I-mfa) is a multifunctional cytosolic protein functioning as...