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Leonard Petrucelli

Explore the profile of Leonard Petrucelli including associated specialties, affiliations and a list of published articles. Areas
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Articles 289
Citations 19893
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Recent Articles
11.
Li Z, Weller C, Shah S, Johnson N, Hao Y, Jarreau P, et al.
Genomics Proteomics Bioinformatics . 2024 Nov; 22(6). PMID: 39576693
Mass spectrometry (MS) is a technique widely employed for the identification and characterization of proteins, with personalized medicine, systems biology, and biomedical applications. The application of MS-based proteomics advances our...
12.
Cruz-Gonzalez G, Meschia J, Madden B, Prudencio M, Polania-Sandoval C, Hartwell J, et al.
JVS Vasc Sci . 2024 Oct; 5:100215. PMID: 39351586
Objective: We sought to identify differentially expressed proteins in serum, plasma, and plaque samples of patients with carotid atherosclerotic lesions. Methods: We performed a systematic review of the proteomic profile...
13.
Vandebergh M, Ramos E, Corriveau-Lecavalier N, Ramanan V, Kornak J, Mester C, et al.
Neurology . 2024 Sep; 103(8):e209832. PMID: 39321401
Background And Objectives: has been proposed as a modifier of disease risk in FTLD-TDP, particularly in pathogenic variant carriers. Furthermore, has been investigated as a disease modifier in the context...
14.
Benatar M, Macklin E, Malaspina A, Rogers M, Hornstein E, Lombardi V, et al.
EBioMedicine . 2024 Sep; 108:105323. PMID: 39270623
Background: With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among...
15.
Benatar M, Macklin E, Malaspina A, Rogers M, Hornstein E, Lombardi V, et al.
medRxiv . 2024 Aug; PMID: 39185513
Background: With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand among the...
16.
Calliari A, Daughrity L, Albagli E, Castellanos Otero P, Yue M, Jansen-West K, et al.
Mol Neurodegener . 2024 Jul; 19(1):56. PMID: 39068448
No abstract available.
17.
Pottier C, Kucukali F, Baker M, Batzler A, Jenkins G, van Blitterswijk M, et al.
medRxiv . 2024 Jul; PMID: 38978643
Frontotemporal lobar degeneration with neuronal inclusions of the TAR DNA-binding protein 43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci identified. We report our...
18.
Todd T, Islam N, Cook C, Caulfield T, Petrucelli L
Neuron . 2024 Jun; 112(14):2269-2288. PMID: 38834068
Neurodegenerative diseases are commonly associated with the formation of aberrant protein aggregates within the brain, and ultrastructural analyses have revealed that the proteins within these inclusions often assemble into amyloid...
19.
Watzlawik J, Hou X, Richardson T, Lewicki S, Siuda J, Wszolek Z, et al.
Autophagy . 2024 May; 20(9):2076-2091. PMID: 38802071
The selective removal of dysfunctional mitochondria, a process termed mitophagy, is critical for cellular health and impairments have been linked to aging, Parkinson disease, and other neurodegenerative conditions. A central...
20.
Pressman P, Carter D, Ramos E, Molden J, Smith K, Dino F, et al.
Neurocase . 2024 May; 30(1):39-47. PMID: 38757415
We present a longitudinal description of a man with the I383V variant of frontotemporal dementia (FTD). His progressive changes in behavior and language resulted in a diagnosis of the right...