Leonard B Maggi Jr
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Explore the profile of Leonard B Maggi Jr including associated specialties, affiliations and a list of published articles.
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28
Citations
2264
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Recent Articles
1.
Antes A, Maggi Jr L
Curr Protoc
. 2021 Mar;
1(3):e86.
PMID: 33751862
Relationships with mentors and labmates are defining aspects of a researcher's journey in science. Ideally, these interactions are outstanding opportunities to learn from others and provide the basis for lifelong...
2.
Antes A, Maggi Jr L
Curr Protoc
. 2021 Mar;
1(3):e87.
PMID: 33740292
Researchers must conduct research responsibly for it to have an impact and to safeguard trust in science. Essential responsibilities of researchers include using rigorous, reproducible research methods, reporting findings in...
3.
Oliveira V, Mahajan N, Bates M, Tripathi C, Kim K, Zaher H, et al.
FASEB Bioadv
. 2020 Feb;
1(7):404-414.
PMID: 32095781
The orphan small nucleolar RNA (snoRNA) ACA11 is overexpressed as a result of the t(4;14) chromosomal translocation in multiple myeloma (MM), increases reactive oxygen species, and drives cell proliferation. Like...
4.
Qiu J, Villa M, Sanin D, Buck M, OSullivan D, Ching R, et al.
Cell Rep
. 2019 May;
27(7):2063-2074.e5.
PMID: 31091446
Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the surrounding microenvironment is therefore key for maintaining appropriate cell...
5.
Kung C, Maggi Jr L, Weber J
Front Endocrinol (Lausanne)
. 2019 Jan;
9:762.
PMID: 30619092
Numerous human diseases arise from alterations of genetic information, most notably DNA mutations. Thought to be merely the intermediate between DNA and protein, changes in RNA sequence were an afterthought...
6.
Wagner A, Devarakonda S, Skidmore Z, Krysiak K, Ramu A, Trani L, et al.
Nat Commun
. 2018 Sep;
9(1):3787.
PMID: 30224629
Nearly all patients with small cell lung cancer (SCLC) eventually relapse with chemoresistant disease. The molecular mechanisms driving chemoresistance in SCLC remain un-characterized. Here, we describe whole-exome sequencing of paired...
7.
Mahajan N, Wu H, Bennett R, Troche C, Licht J, Weber J, et al.
FASEB J
. 2017 Feb;
31(2):482-490.
PMID: 28148777
Overexpression of the multiple myeloma set domain (MMSET) Wolf-Hirschhorn syndrome candidate 1 gene, which contains an orphan box H/ACA class small nucleolar RNA, ACA11, in an intron, is associated with...
8.
Maggi Jr L, Weber J
Breast Cancer Res
. 2015 Apr;
17:51.
PMID: 25888162
With tremendous advances in sequencing and analysis in recent years, a wealth of genetic information has become available to identify and classify breast cancer into five main subtypes - luminal...
9.
Forys J, Kuzmicki C, Saporita A, Winkeler C, Maggi Jr L, Weber J
Cell Rep
. 2014 Apr;
7(2):514-526.
PMID: 24726362
The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellular transformation in response to various oncogenic signals. Here, we show that loss of...
10.
Maggi Jr L, Winkeler C, Miceli A, Apicelli A, Brady S, Kuchenreuther M, et al.
Biochim Biophys Acta
. 2014 Feb;
1842(6):831-9.
PMID: 24525025
Since its discovery close to twenty years ago, the ARF tumor suppressor has played a pivotal role in the field of cancer biology. Elucidating ARF's basal physiological function in the...