Crystal L Winkeler
Overview
Explore the profile of Crystal L Winkeler including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
142
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0
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Recent Articles
1.
Forys J, Kuzmicki C, Saporita A, Winkeler C, Maggi Jr L, Weber J
Cell Rep
. 2014 Apr;
7(2):514-526.
PMID: 24726362
The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellular transformation in response to various oncogenic signals. Here, we show that loss of...
2.
Maggi Jr L, Winkeler C, Miceli A, Apicelli A, Brady S, Kuchenreuther M, et al.
Biochim Biophys Acta
. 2014 Feb;
1842(6):831-9.
PMID: 24525025
Since its discovery close to twenty years ago, the ARF tumor suppressor has played a pivotal role in the field of cancer biology. Elucidating ARF's basal physiological function in the...
3.
Winkeler C, Kladney R, Maggi Jr L, Weber J
PLoS One
. 2012 Aug;
7(7):e42005.
PMID: 22860046
Osteoclasts are terminally differentiated cells that attach to bone and secrete proteases to degrade the bone matrix. The primary protease responsible for the degradation of the organic component of the...
4.
Saporita A, Chang H, Winkeler C, Apicelli A, Kladney R, Wang J, et al.
Cancer Res
. 2011 Sep;
71(21):6708-17.
PMID: 21937682
The p19ARF tumor suppressor limits ribosome biogenesis and responds to hyperproliferative signals to activate the p53 checkpoint response. Although its activation of p53 has been well characterized, the role of...