Lennice K Castro
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Explore the profile of Lennice K Castro including associated specialties, affiliations and a list of published articles.
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6
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51
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Recent Articles
1.
Vicary A, Jordan S, Mendes M, Swaminath S, Castro L, Porter J, et al.
bioRxiv
. 2024 Nov;
PMID: 39605461
Transcription of interferons upon viral infection is critical for cell-intrinsic innate immunity. This process is influenced by many host and viral factors. To identify host factors that modulate interferon induction...
2.
Castro L, Daugherty M
Curr Opin Immunol
. 2023 Jun;
83:102354.
PMID: 37311351
Host innate immune sensors are vital for the initial detection of pathogen infection. Such sensors thus need to constantly adapt in escalating evolutionary arms races with pathogens. Recently, two inflammasome-forming...
3.
Tsu B, Agarwal R, Gokhale N, Kulsuptrakul J, Ryan A, Fay E, et al.
PLoS Biol
. 2023 Jun;
21(6):e3002144.
PMID: 37289745
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find that the 3CL...
4.
Tsu B, Agarwal R, Gokhale N, Kulsuptrakul J, Ryan A, Castro L, et al.
bioRxiv
. 2022 Sep;
PMID: 36172130
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find that the 3CL...
5.
Guzzo M, Sanderlin A, Castro L, Laub M
Dev Cell
. 2021 Jul;
56(15):2145-2159.e7.
PMID: 34242584
In every organism, the cell cycle requires the execution of multiple processes in a strictly defined order. However, the mechanisms used to ensure such order remain poorly understood, particularly in...
6.
Guzzo M, Castro L, Reisch C, Guo M, Laub M
mBio
. 2020 Jan;
11(1).
PMID: 31937638
CRISPR interference (CRISPRi) is a powerful new tool used in different organisms that provides a fast, specific, and reliable way to knock down gene expression. is a well-studied model bacterium,...