Lauren Ambrogio
Overview
Explore the profile of Lauren Ambrogio including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
6939
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0
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Recent Articles
1.
Notay M, Saric-Bosanac S, Vaughn A, Dhaliwal S, Trivedi M, Reiter P, et al.
J Cosmet Dermatol
. 2019 Jul;
19(3):689-693.
PMID: 31257694
Background: Both topical and oral probiotics are becoming widely used. There is increasing interest in the cosmetic potential in topical probiotics. Nitrosomonas eutropha is an ammonia-oxidizing bacteria. Aim: The purpose...
2.
Perry J, Kiezun A, Tonzi P, Van Allen E, Carter S, Baca S, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
111(51):E5564-73.
PMID: 25512523
Osteosarcoma is the most common primary bone tumor, yet there have been no substantial advances in treatment or survival in three decades. We examined 59 tumor/normal pairs by whole-exome, whole-genome,...
3.
Crompton B, Stewart C, Taylor-Weiner A, Alexe G, Kurek K, Calicchio M, et al.
Cancer Discov
. 2014 Sep;
4(11):1326-41.
PMID: 25186949
Unlabelled: Pediatric Ewing sarcoma is characterized by the expression of chimeric fusions of EWS and ETS family transcription factors, representing a paradigm for studying cancers driven by transcription factor rearrangements....
4.
Shern J, Chen L, Chmielecki J, Wei J, Patidar R, Rosenberg M, et al.
Cancer Discov
. 2014 Jan;
4(2):216-31.
PMID: 24436047
Unlabelled: Despite gains in survival, outcomes for patients with metastatic or recurrent rhabdomyosarcoma remain dismal. In a collaboration between the National Cancer Institute, Children's Oncology Group, and Broad Institute, we...
5.
Ojesina A, Lichtenstein L, Freeman S, Pedamallu C, Imaz-Rosshandler I, Pugh T, et al.
Nature
. 2014 Jan;
506(7488):371-5.
PMID: 24390348
Cervical cancer is responsible for 10-15% of cancer-related deaths in women worldwide. The aetiological role of infection with high-risk human papilloma viruses (HPVs) in cervical carcinomas is well established. Previous...
6.
Lawrence M, Stojanov P, Polak P, Kryukov G, Cibulskis K, Sivachenko A, et al.
Nature
. 2013 Jun;
499(7457):214-218.
PMID: 23770567
Major international projects are underway that are aimed at creating a comprehensive catalogue of all the genes responsible for the initiation and progression of cancer. These studies involve the sequencing...
7.
Chmielecki J, Crago A, Rosenberg M, OConnor R, Walker S, Ambrogio L, et al.
Nat Genet
. 2013 Jan;
45(2):131-2.
PMID: 23313954
Solitary fibrous tumors (SFTs) are rare mesenchymal tumors. Here, we describe the identification of a NAB2-STAT6 fusion from whole-exome sequencing of 17 SFTs. Analysis in 53 tumors confirmed the presence...
8.
Greulich H, Kaplan B, Mertins P, Chen T, Tanaka K, Yun C, et al.
Proc Natl Acad Sci U S A
. 2012 Aug;
109(36):14476-81.
PMID: 22908275
We assessed somatic alleles of six receptor tyrosine kinase genes mutated in lung adenocarcinoma for oncogenic activity. Five of these genes failed to score in transformation assays; however, novel recurring...
9.
Lee R, Stewart C, Carter S, Ambrogio L, Cibulskis K, Sougnez C, et al.
J Clin Invest
. 2012 Jul;
122(8):2983-8.
PMID: 22797305
Cancer is principally considered a genetic disease, and numerous mutations are thought essential to drive its growth. However, the existence of genomically stable cancers and the emergence of mutations in...
10.
Berger M, Hodis E, Heffernan T, Deribe Y, Lawrence M, Protopopov A, et al.
Nature
. 2012 May;
485(7399):502-6.
PMID: 22622578
Melanoma is notable for its metastatic propensity, lethality in the advanced setting and association with ultraviolet exposure early in life. To obtain a comprehensive genomic view of melanoma in humans,...