Laura N Burga
Overview
Explore the profile of Laura N Burga including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
791
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0
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Recent Articles
1.
Hills F, Jorge F, Burga L, Bostina M
Curr Protoc
. 2025 Mar;
5(3):e70115.
PMID: 40056094
Coronaviridae spike glycoproteins mediate viral entry and fusion to host cells through binding to host receptors (i.e., ACE2, DPP4) and are key components in determining viral host range, making them...
2.
Hills F, Eruera A, Hodgkinson-Bean J, Jorge F, Easingwood R, Brown S, et al.
PLoS Pathog
. 2024 May;
20(5):e1012158.
PMID: 38805567
SARS-CoV-2 is the third known coronavirus (CoV) that has crossed the animal-human barrier in the last two decades. However, little structural information exists related to the close genetic species within...
3.
Jadav N, Velamoor S, Huang D, Cassin L, Hazelton N, Eruera A, et al.
J Struct Biol
. 2023 Oct;
215(4):108035.
PMID: 37805154
The advent of volume electron microscopy (vEM) has provided unprecedented insights into cellular and subcellular organization, revolutionizing our understanding of cancer biology. This study presents a previously unexplored comparative analysis...
4.
Waqqar S, Lee K, Lawley B, Bilton T, Quinones-Mateu M, Bostina M, et al.
Cancers (Basel)
. 2023 May;
15(9).
PMID: 37174006
The Seneca Valley virus (SVV) is an oncolytic virus from the picornavirus family, characterized by a 7.3-kilobase RNA genome encoding for all the structural and functional viral proteins. Directed evolution...
5.
Jayawardena N, McCarthy C, Wang I, Waqqar S, Burga L, Strauss M, et al.
Virology
. 2022 Sep;
575:74-82.
PMID: 36084546
Seneca Valley virus (SVV) is a newly discovered picornavirus in the Senecavirus genus. SVV-001 strain has shown promise as an oncolytic virus against tumors with neuroendocrine features. There is a...
6.
Jayawardena N, Miles L, Burga L, Rudin C, Wolf M, Poirier J, et al.
Viruses
. 2021 Apr;
13(5).
PMID: 33924774
Seneca Valley virus (SVV) is a picornavirus with potency in selectively infecting and lysing cancerous cells. The cellular receptor for SVV mediating the selective tropism for tumors is anthrax toxin...
7.
Velamoor S, Mitchell A, Humbel B, Kim W, Pushparajan C, Visnovsky G, et al.
mBio
. 2020 Aug;
11(4).
PMID: 32788378
Enveloped viruses hijack cellular membranes in order to provide the necessary material for virion assembly. In particular, viruses that replicate and assemble inside the nucleus have developed special approaches to...
8.
Jayawardena N, Poirier J, Burga L, Bostina M
Oncolytic Virother
. 2020 Mar;
9:1-15.
PMID: 32185149
Oncolytic viruses (OVs) are replication competent agents that selectively target cancer cells. After penetrating the tumor cell, viruses replicate and eventually trigger cell lysis, releasing the new viral progeny, which...
9.
McCarthy C, Jayawardena N, Burga L, Bostina M
Cancers (Basel)
. 2020 Mar;
12(3).
PMID: 32121046
The authors wish to make the following corrections to this paper [1] [...].
10.
Jayawardena N, Burga L, Poirier J, Bostina M
Oncolytic Virother
. 2019 Nov;
8:39-56.
PMID: 31754615
Recent advancements in oncolytic virotherapy commend a special attention to developing new strategies for targeting cancer cells with oncolytic viruses (OVs). Modifications of the viral envelope or coat proteins serve...