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Gerburg M Wulf

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Articles 64
Citations 2886
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Recent Articles
1.
Lei J, Dobrolecki L, Huang C, Srinivasan R, Vasaikar S, Lewis A, et al.
bioRxiv . 2024 Dec; PMID: 39713418
Combination chemotherapy remains essential for clinical management of triple-negative breast cancer (TNBC). Consequently, responses to multiple single agents cannot be delineated at the single patient level, even though some patients...
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Mohd O, Heng Y, Wang L, Thavamani A, Massicott E, Wulf G, et al.
Anal Chem . 2024 Jul; 96(31):12729-12738. PMID: 39044395
MicroRNAs (miRNAs) are small RNAs that are often dysregulated in many diseases, including cancers. They are highly tissue-specific and stable, thus, making them particularly useful as biomarkers. As the spatial...
3.
Heng Y, Baker G, Fein-Zachary V, Guzman-Arocho Y, Bret-Mounet V, Massicott E, et al.
Breast Cancer Res . 2024 Jul; 26(1):109. PMID: 38956693
Background: The effect of gender-affirming testosterone therapy (TT) on breast cancer risk is unclear. This study investigated the association between TT and breast tissue composition and breast tissue density in...
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Guo Z, Luo J, Mashl R, Hoog J, Maiti P, Fettig N, et al.
Cancer Res Commun . 2024 May; 4(6):1430-1440. PMID: 38717161
Significance: In this research, we demonstrated that the pan-PI3K inhibitor copanlisib enhanced the cytotoxicity of eribulin in a panel of TNBC PDX models. The improved tumor growth inhibition was irrespective...
6.
Ke S, Dang F, Wang L, Chen J, Naik M, Li W, et al.
Nat Commun . 2024 Apr; 15(1):3220. PMID: 38622115
Induced oncoproteins degradation provides an attractive anti-cancer modality. Activation of anaphase-promoting complex (APC/C) prevents cell-cycle entry by targeting crucial mitotic proteins for degradation. Phosphorylation of its co-activator CDH1 modulates the...
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Heng Y, Baker G, Fein-Zachary V, Guzman-Arocho Y, Bret-Mounet V, Massicott E, et al.
medRxiv . 2024 Jan; PMID: 38260574
Objective: Determine the association between TT and breast tissue composition and breast tissue density in trans masculine individuals (TMIs). Design: This is a cross-sectional study. Setting: TMIs (n=444) underwent chest-contouring...
8.
Patterson-Fortin J, Jadhav H, Pantelidou C, Phan T, Grochala C, Mehta A, et al.
Nat Commun . 2023 Dec; 14(1):8193. PMID: 38081854
No abstract available.
9.
Batalini F, Madison R, Sokol E, Jin D, Chen K, Decker B, et al.
JCO Precis Oncol . 2023 Nov; 7:e2300091. PMID: 37992259
Purpose: Poly ADP-ribose polymerase inhibitors (PARPi) are approved for patients with human epidermal growth factor receptor 2-negative metastatic breast cancer (mBC) and germline pathogenic/likely pathogenic variant (hereafter mutation) in the...
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Varkaris A, Fece de la Cruz F, Martin E, Norden B, Chevalier N, Kehlmann A, et al.
Cancer Discov . 2023 Nov; 14(2):227-239. PMID: 37916958
Significance: In one of the largest patient cohorts analyzed to date, this study defines the clinical landscape of acquired resistance to PI3Kα inhibitors. Genomic alterations within the PI3K pathway represent...