Laura Marquez-Exposito
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Explore the profile of Laura Marquez-Exposito including associated specialties, affiliations and a list of published articles.
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27
Citations
534
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Recent Articles
11.
Tejera-Munoz A, Marquez-Exposito L, Tejedor-Santamaria L, Rayego-Mateos S, Orejudo M, Suarez-Alvarez B, et al.
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008801
The cellular communication network factor 2 (CCN2/CTGF) has been traditionally described as a mediator of the fibrotic responses induced by other factors including the transforming growth factor β (TGF-β). However,...
12.
Valentijn F, Knoppert S, Pissas G, Rodrigues-Diez R, Marquez-Exposito L, Broekhuizen R, et al.
Antioxidants (Basel)
. 2021 Dec;
10(12).
PMID: 34943123
AKI, due to the fact of altered oxygen supply after kidney transplantation, is characterized by renal ischemia-reperfusion injury (IRI). Recent data suggest that AKI to CKD progression may be driven...
13.
Rayego-Mateos S, Campillo S, Rodrigues-Diez R, Tejera-Munoz A, Marquez-Exposito L, Goldschmeding R, et al.
Clin Sci (Lond)
. 2021 Aug;
135(16):1999-2029.
PMID: 34427291
Chronic kidney disease (CKD) is characterized by pathological accumulation of extracellular matrix (ECM) proteins in renal structures. Tubulointerstitial fibrosis is observed in glomerular diseases as well as in the regeneration...
14.
Cantero-Navarro E, Rayego-Mateos S, Orejudo M, Tejedor-Santamaria L, Tejera-Munoz A, Sanz A, et al.
Front Med (Lausanne)
. 2021 Jul;
8:688060.
PMID: 34307414
Inflammation is a key characteristic of kidney disease, but this immune response is two-faced. In the acute phase of kidney injury, there is an activation of the immune cells to...
15.
Marquez-Exposito L, Tejedor-Santamaria L, Santos-Sanchez L, Valentijn F, Cantero-Navarro E, Rayego-Mateos S, et al.
Front Pharmacol
. 2021 Jul;
12:662020.
PMID: 34239439
Acute kidney injury (AKI) is more frequent in elderly patients. Mechanisms contributing to AKI (tubular cell death, inflammatory cell infiltration, impaired mitochondrial function, and prolonged cell-cycle arrest) have been linked...
16.
Rodrigues-Diez R, Tejera-Munoz A, Orejudo M, Marquez-Exposito L, Santos L, Rayego-Mateos S, et al.
Nefrologia (Engl Ed)
. 2021 Mar;
41(3):244-257.
PMID: 33775443
Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by cells of the immune system, predominantly Th17 lymphocytes and γδ lymphocytes. In this paper, we review the role of IL-17A in the...
17.
Miguel V, Tituana J, Herrero J, Herrero L, Serra D, Cuevas P, et al.
J Clin Invest
. 2021 Jan;
131(5).
PMID: 33465052
Chronic kidney disease (CKD) remains a major epidemiological, clinical, and biomedical challenge. During CKD, renal tubular epithelial cells (TECs) present a persistent inflammatory and profibrotic response. Fatty acid oxidation (FAO),...
18.
Marquez-Exposito L, Rodrigues-Diez R, Rayego-Mateos S, Fierro-Fernandez M, Rodrigues-Diez R, Orejudo M, et al.
FASEB J
. 2020 Dec;
35(1):e21213.
PMID: 33368614
Preclinical studies have demonstrated that activation of the NOTCH pathway plays a key role in the pathogenesis of kidney damage. There is currently no information on the role of the...
19.
Marchant V, Tejera-Munoz A, Marquez-Exposito L, Rayego-Mateos S, Rodrigues-Diez R, Tejedor L, et al.
Biomolecules
. 2020 Sep;
10(10).
PMID: 32987705
Chronic kidney disease (CKD) is a health problem reaching epidemic proportions. There is no cure for CKD, and patients may progress to end-stage renal disease (ESRD). Peritoneal dialysis (PD) is...
20.
Rodrigues-Diez R, Tejera-Munoz A, Marquez-Exposito L, Rayego-Mateos S, Santos Sanchez L, Marchant V, et al.
Br J Pharmacol
. 2020 Jun;
177(21):4873-4886.
PMID: 32562276
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has overwhelmed healthcare systems requiring the rapid development of treatments, at least, to reduce COVID-19 severity. Drug...