Macarena Orejudo
Overview
Explore the profile of Macarena Orejudo including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
347
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0
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Recent Articles
1.
Baldan-Martin M, Rubin de Celix C, Orejudo M, Ortega Moreno L, Fernandez-Tome S, Soleto I, et al.
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958675
Biological therapies only benefit one-third of patients with Crohn's disease (CD). For this reason, a deeper understanding of the mechanisms by which biologics elicit their effect on intestinal mucosa is...
2.
Soleto I, Ramirez C, Gomez C, Baldan-Martin M, Orejudo M, Mercado J, et al.
Biomedicines
. 2023 Oct;
11(10).
PMID: 37893204
Inflammatory bowel disease (IBD) is a chronic condition which includes ulcerative colitis (UC) and Crohn's disease (CD), the origins of which are not yet fully understood. Both conditions involve an...
3.
Jimenez-Castilla L, Opazo-Rios L, Marin-Royo G, Orejudo M, Rodrigues-Diez R, Ballesteros-Martinez C, et al.
Antioxidants (Basel)
. 2022 Dec;
11(12).
PMID: 36552707
In diabetes, chronic hyperglycemia, dyslipidemia, inflammation and oxidative stress contribute to the progression of macro/microvascular complications. Recently, benefits of the use of flavonoids in these conditions have been established. This...
4.
Rodrigues-Diez R, Tejera-Munoz A, Orejudo M, Marquez-Exposito L, Santos-Sanchez L, Rayego-Mateos S, et al.
Nefrologia (Engl Ed)
. 2022 Sep;
41(3):244-257.
PMID: 36166242
Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by cells of the immune system, predominantly Th17 and γδ lymphocytes. In this paper, we review the role of IL-17A in the pathogenesis...
5.
Opazo-Rios L, Soto-Catalan M, Lazaro I, Sala-Vila A, Jimenez-Castilla L, Orejudo M, et al.
Int J Mol Sci
. 2022 Apr;
23(7).
PMID: 35409324
Metabolic associated fatty liver disease (MAFLD) is a hepatic manifestation of metabolic syndrome and usually associated with obesity and diabetes. Our aim is to characterize the pathophysiological mechanism involved in...
6.
Rodrigues-Diez R, Tejera-Munoz A, Esteban V, Steffensen L, Rodrigues-Diez R, Orejudo M, et al.
Hypertension
. 2022 Feb;
79(3):e42-e55.
PMID: 35138869
Background: CCN2 (cellular communication network factor 2) is a matricellular protein involved in cell communication and microenvironmental signaling responses. CCN2 is known to be overexpressed in several cardiovascular diseases, but...
7.
Tejera-Munoz A, Marquez-Exposito L, Tejedor-Santamaria L, Rayego-Mateos S, Orejudo M, Suarez-Alvarez B, et al.
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008801
The cellular communication network factor 2 (CCN2/CTGF) has been traditionally described as a mediator of the fibrotic responses induced by other factors including the transforming growth factor β (TGF-β). However,...
8.
Jimenez-Castilla L, Marin-Royo G, Orejudo M, Opazo-Rios L, Caro-Ordieres T, Artaiz I, et al.
Antioxidants (Basel)
. 2021 Dec;
10(12).
PMID: 34943023
Diabetes mellitus (DM) is a high-impact disease commonly characterized by hyperglycemia, inflammation, and oxidative stress. Diabetic nephropathy (DN) is a common diabetic microvascular complication and the leading cause of chronic...
9.
Cantero-Navarro E, Rayego-Mateos S, Orejudo M, Tejedor-Santamaria L, Tejera-Munoz A, Sanz A, et al.
Front Med (Lausanne)
. 2021 Jul;
8:688060.
PMID: 34307414
Inflammation is a key characteristic of kidney disease, but this immune response is two-faced. In the acute phase of kidney injury, there is an activation of the immune cells to...
10.
Rodrigues-Diez R, Tejera-Munoz A, Orejudo M, Marquez-Exposito L, Santos L, Rayego-Mateos S, et al.
Nefrologia (Engl Ed)
. 2021 Mar;
41(3):244-257.
PMID: 33775443
Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by cells of the immune system, predominantly Th17 lymphocytes and γδ lymphocytes. In this paper, we review the role of IL-17A in the...