Lars Herfindal
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Explore the profile of Lars Herfindal including associated specialties, affiliations and a list of published articles.
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67
Citations
425
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Recent Articles
11.
Bjornstad R, Nerbo Reiten I, Knudsen K, Schjott J, Herfindal L
Int J Pharm
. 2022 Nov;
629:122379.
PMID: 36370997
Anthracyclines such as doxorubicin (Dox) are the preferred chemotherapeutics for several cancers. However, Dox-induced cardiotoxicity limits its therapeutic potential. Liposomal encapsulation of Dox has been used for patients with risk...
12.
Forde J, Nerbo Reiten I, Fladmark K, Olsnes Kittang A, Herfindal L
Biol Open
. 2022 Nov;
11(12).
PMID: 36355409
Acute myeloid leukemia and myelodysplastic syndromes are cancers of the bone marrow with poor prognosis in frail and older patients. To investigate cancer pathophysiology and therapies, confocal imaging of fluorescent...
13.
Alhourani A, Forde J, Nasrollahzadeh M, Eichacker L, Herfindal L, Hagland H
Nanoscale Adv
. 2022 Sep;
4(6):1668-1680.
PMID: 36134366
Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the...
14.
Auvert E, Aesoy R, Giraud F, Herfindal L, Anizon F, Moreau P
Bioorg Med Chem Lett
. 2022 Aug;
73:128914.
PMID: 35917834
We synthesized new analogues of the anti-AML agent VS-II-173. We studied the effect of the substitution at the 1- and 5-positions of the pyrazolo[4,3-a]phenanthridine scaffold on Pim-1 kinase inhibition and...
15.
Slimestad R, Rathe B, Aesoy R, Carpinteyro Diaz A, Herfindal L, Fossen T
Sci Rep
. 2022 May;
12(1):7805.
PMID: 35551255
Garden chervil, Anthriscus cerefolium (L.) Hoffm. is an important herb commonly applied in Norwegian large-scale commercial kitchens. This species is a highly enriched source of phenolics, containing 1260 mg gallic...
16.
Gundersen E, Forde J, Tislevoll B, Leitch C, Barratt G, Gjertsen B, et al.
Int J Pharm
. 2021 Nov;
612:121296.
PMID: 34793932
Treatment of acute myeloid leukaemia (AML) relies on decades-old drugs, and while recent years have seen some breakthroughs, AML is still characterised by poor prognosis and survival rate. Drug repurposing...
17.
Alhourani A, Forde J, Eichacker L, Herfindal L, Hagland H
ACS Omega
. 2021 Oct;
6(38):24619-24629.
PMID: 34604644
Graphene-based drug carriers provide a promising addition to current cancer drug delivery options. Increased accessibility of high-quality graphene made by plasma-enhanced chemical vapor deposition (PE-CVD) makes it an attractive material...
18.
Fewer D, Jokela J, Heinila L, Aesoy R, Sivonen K, Galica T, et al.
Physiol Plant
. 2021 Jun;
173(2):639-650.
PMID: 34145585
Cyanobacteria produce a variety of chemically diverse cyclic lipopeptides with potent antifungal activities. These cyclic lipopeptides have an amphipathic structure comprised of a polar peptide cycle and hydrophobic fatty acid...
19.
Viktorsson E, Aesoy R, Stoa S, Lekve V, Doskeland S, Herfindal L, et al.
RSC Med Chem
. 2021 Jun;
12(5):767-778.
PMID: 34124675
Novel chemotherapeutic strategies for acute myeloid leukemia (AML) treatment are called for. We have recently demonstrated that the phenazine 5,10-dioxide natural products iodinin () and myxin () exhibit potent and...
20.
Skjanes K, Aesoy R, Herfindal L, Skomedal H
Physiol Plant
. 2021 Jun;
173(2):612-623.
PMID: 34085279
In addition to the rapidly expanding field of using microalgae for food and feed, microalgae represent a tremendous potential for new bioactive compounds with health-promoting effects. One field where new...