Lars Hellman
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Explore the profile of Lars Hellman including associated specialties, affiliations and a list of published articles.
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110
Citations
1563
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Recent Articles
11.
Ramos-Ramirez P, Liu J, Mogren S, Gregory J, Noreby M, Petren A, et al.
J Immunol Res
. 2023 Feb;
2023:9393497.
PMID: 36761882
Background: Asthma is a chronic inflammatory disease with structural changes in the lungs defined as airway remodelling. Mast cell responses are important in asthma as they, upon activation, release mediators...
12.
Akula S, Riihimaki M, Waern I, Abrink M, Raine A, Hellman L, et al.
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430453
Asthma is a chronic inflammatory airway disease and a serious health problem in horses as well as in humans. In humans and mice, mast cells (MCs) are known to be...
13.
Hellman L, Akula S, Fu Z, Wernersson S
Front Immunol
. 2022 Jul;
13:918305.
PMID: 35865537
Proteases are stored in very large amounts within abundant cytoplasmic granules of mast cells (MCs), and in lower amounts in basophils. These proteases are stored in their active form in...
14.
Akula S, Lara S, Olsson A, Hellman L
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628628
Cell lines of monocyte/macrophage origin are often used as model systems to study monocyte/macrophage biology. A relevant question is how similar these cell lines are to their in vivo counterparts?...
15.
Zhang Y, Doulabi E, Herre M, Cedervall J, Qiao Q, Miao Z, et al.
Cancers (Basel)
. 2022 Apr;
14(8).
PMID: 35454853
Platelets constitute a major reservoir of platelet-derived growth factor B (PDGFB) and are continuously activated in the tumor microenvironment, exposing tumors to the plethora of growth factors contained in platelet...
16.
Lara S, Akula S, Fu Z, Olsson A, Kleinau S, Hellman L
Int J Mol Sci
. 2022 Apr;
23(7).
PMID: 35409250
Monocytes were previously thought to be the precursors of all tissue macrophages but have recently been found to represent a unique population of cells, distinct from the majority of tissue...
17.
Femel J, van Hooren L, Herre M, Cedervall J, Saupe F, Huijbers E, et al.
Cancer Immunol Immunother
. 2022 Feb;
71(10):2581.
PMID: 35226107
No abstract available.
18.
Paivandy A, Akula S, Lara S, Fu Z, Olsson A, Kleinau S, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163105
To obtain a more detailed picture of macrophage (MΦ) biology, in the current study, we analyzed the transcriptome of mouse peritoneal MΦs by RNA-seq and PCR-based transcriptomics. The results show...
19.
Femel J, van Hooren L, Herre M, Cedervall J, Saupe F, Huijbers E, et al.
Cancer Immunol Immunother
. 2022 Jan;
71(8):2029-2040.
PMID: 35018481
Galectin-1 (Gal1) is a glycan-binding protein that promotes tumor progression by several distinct mechanisms. Through direct binding to vascular endothelial growth factor (VEGF)-receptor 2, Gal1 is able to induce VEGF-like...
20.
Fu Z, Akula S, Olsson A, Hellman L
Dev Comp Immunol
. 2021 Dec;
129:104337.
PMID: 34919980
Serine proteases are major granule constituents of cells from several mammalian hematopoietic cell lineages. Despite the relatively extensive knowledge about these mammalian proteases, very little is known about their bird,...