Lars Bohlin
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Explore the profile of Lars Bohlin including associated specialties, affiliations and a list of published articles.
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52
Citations
945
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Recent Articles
1.
Svahn K, Chryssanthou E, Olsen B, Bohlin L, Goransson U
Fungal Biol Biotechnol
. 2017 Sep;
2:1.
PMID: 28955453
Background: The need for new antibiotic drugs increases as pathogenic microorganisms continue to develop resistance against current antibiotics. We obtained samples from Antarctica as part of a search for new...
2.
Bohlin L, Cardenas P, Backlund A, Goransson U
Prog Mol Subcell Biol
. 2017 Feb;
55:1-34.
PMID: 28238034
Currents efforts in marine biodiscovery have essentially focused on temperate to tropical shallow water organisms. With more than 6000 species of marine plants and animals, the Kosterfjord area has the...
3.
Carstens B, Rosengren K, Gunasekera S, Schempp S, Bohlin L, Dahlstrom M, et al.
J Nat Prod
. 2015 Jul;
78(8):1886-93.
PMID: 26222779
Two disulfide-containing peptides, barrettides A (1) and B (2), from the cold-water marine sponge Geodia barretti are described. Those 31 amino acid residue long peptides were sequenced using mass spectrometry...
4.
Wang L, Gao S, Jiang W, Luo C, Xu M, Bohlin L, et al.
Int J Mol Sci
. 2014 Sep;
15(9):16226-45.
PMID: 25226533
Many dietary compounds are known to have health benefits owing to their antioxidative and anti-inflammatory properties. To determine the molecular mechanism of these food-derived compounds, we analyzed their effect on...
5.
Stromstedt A, Felth J, Bohlin L
Phytochem Anal
. 2013 Sep;
25(1):13-28.
PMID: 24019222
Introduction: Identifying bioactive molecules from complex biomasses requires careful selection and execution of relevant bioassays in the various stages of the discovery process of potential leads and targets. Objective: The...
6.
Li Y, Frenz C, Li Z, Chen M, Wang Y, Li F, et al.
Chem Biol Drug Des
. 2013 Mar;
81(4):537-44.
PMID: 23534413
Synthetic drugs such as allopurinol and benzbromarone are commonly used to treat the complex pathogenesis of gout, a metabolic disease that results from an inflammation of the joints caused by...
7.
Felth J, Lesiak-Mieczkowska K, Darcy P, Haglund C, Gullbo J, Larsson R, et al.
Invest New Drugs
. 2012 Nov;
31(3):587-98.
PMID: 23179339
Gambogic acid (GA), displays cytotoxicity towards a wide variety of tumor cells and has been shown to affect many important cell-signaling pathways. In the present work, we investigated the mechanism...
8.
Svahn K, Goransson U, El-Seedi H, Bohlin L, Larsson D, Olsen B, et al.
Infect Ecol Epidemiol
. 2012 Sep;
2.
PMID: 22957125
Background: Filamentous fungi are well known for their production of substances with antimicrobial activities, several of which have formed the basis for the development of new clinically important antimicrobial agents....
9.
El-Seedi H, El-Said A, Khalifa S, Goransson U, Bohlin L, Borg-Karlson A, et al.
J Agric Food Chem
. 2012 Aug;
60(44):10877-95.
PMID: 22931195
Hydroxycinnamic acids are the most widely distributed phenolic acids in plants. Broadly speaking, they can be defined as compounds derived from cinnamic acid. They are present at high concentrations in...
10.
Ruhaak L, Felth J, Karlsson P, Rafter J, Verpoorte R, Bohlin L
Biol Pharm Bull
. 2011 May;
34(5):774-8.
PMID: 21532172
Cyclooxygenase enzymes (COX-1 and COX-2) catalyse the production of prostaglandins from arachidonic acid. Prostaglandins are important mediators in the inflammatory process and their production can be reduced by COX-inhibitors. Endocannabinoids,...