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Laramie Duncan

Explore the profile of Laramie Duncan including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 4044
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Recent Articles
1.
Zhou B, Arthur J, Guo H, Kim T, Huang Y, Pattni R, et al.
Cell . 2024 Oct; 187(23):6687-6706.e25. PMID: 39353437
Complex structural variations (cxSVs) are often overlooked in genome analyses due to detection challenges. We developed ARC-SV, a probabilistic and machine-learning-based method that enables accurate detection and reconstruction of cxSVs...
2.
Schulmann A, Feng N, Auluck P, Mukherjee A, Komal R, Leng Y, et al.
bioRxiv . 2024 Sep; PMID: 39282422
The mediodorsal thalamus (MD) and adjacent midline nuclei are important for cognition and mental illness, but their cellular composition is not well defined. Using single-nucleus and spatial transcriptomics, we identified...
3.
Juvinao-Quintero D, Kunzel R, Larrabure-Torrealva G, Duncan L, Kirschbaum C, Sanchez S, et al.
Psychoneuroendocrinology . 2024 Jun; 167:107089. PMID: 38850884
Background: The hypothalamic pituitary adrenal (HPA) axis is a system involved in stress and pregnancy regulation, and hair cortisol concentration (HCC) is a promising biomarker of its activity. Assessing factors...
4.
Juvinao-Quintero D, Kunzel R, Larabure-Torrealva G, Duncan L, Kirschbaum C, Sanchez S, et al.
Res Sq . 2023 Oct; PMID: 37790441
Assessing factors that influence chronic stress biomarkers like hair cortisol concentrations (HCCs) in pregnancy is critical to prevent adverse pregnancy outcomes. Thus, we aimed to identify correlates of HCC preconception...
5.
Tan L, Shi J, Moghadami S, Parasar B, Wright C, Seo Y, et al.
Science . 2023 Sep; 381(6662):1112-1119. PMID: 37676945
The cerebellum contains most of the neurons in the human brain and exhibits distinctive modes of development and aging. In this work, by developing our single-cell three-dimensional (3D) genome assay-diploid...
6.
Zhu X, Zhou B, Pattni R, Gleason K, Tan C, Kalinowski A, et al.
Nat Neurosci . 2023 Aug; 26(10):1833. PMID: 37648813
No abstract available.
7.
Duncan L, Deisseroth K
Neuropsychopharmacology . 2023 Jul; 49(1):276-281. PMID: 37422511
Psychiatric diseases are strongly influenced by genetics, but genetically guided treatments have been slow to develop, and precise molecular mechanisms remain mysterious. Although individual locations in the genome tend to...
8.
Tan L, Shi J, Moghadami S, Wright C, Parasar B, Seo Y, et al.
bioRxiv . 2023 Mar; PMID: 36865235
The cerebellum contains most of the neurons in the human brain, and exhibits unique modes of development, malformation, and aging. For example, granule cells-the most abundant neuron type-develop unusually late...
9.
Duncan L, Shen H, Schulmann A, Li T, Kolachana B, Mandal A, et al.
Neuropsychopharmacology . 2023 Jan; 48(5):764-772. PMID: 36694041
A new era of human postmortem tissue research has emerged thanks to the development of 'omics technologies that measure genes, proteins, and spatial parameters in unprecedented detail. Also newly possible...
10.
Zhu X, Zhou B, Pattni R, Gleason K, Tan C, Kalinowski A, et al.
Nat Neurosci . 2021 Jan; 24(2):186-196. PMID: 33432196
Retrotransposons can cause somatic genome variation in the human nervous system, which is hypothesized to have relevance to brain development and neuropsychiatric disease. However, the detection of individual somatic mobile...