Lakshmi K Matukumalli
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Explore the profile of Lakshmi K Matukumalli including associated specialties, affiliations and a list of published articles.
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2965
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Recent Articles
1.
Lei M, Matukumalli L, Arora K, Weber N, Malashock R, Mao F, et al.
Brief Bioinform
. 2024 Oct;
25(Supplement_1).
PMID: 39376084
Biomedical data are growing exponentially in both volume and levels of complexity, due to the rapid advancement of technologies and research methodologies. Analyzing these large datasets, referred to collectively as...
2.
Salomon-Torres R, Matukumalli L, Van Tassell C, Villa-Angulo C, Gonzalez-Vizcarra V, Villa-Angulo R
PLoS One
. 2014 Jul;
9(7):e103046.
PMID: 25050984
Genomic structural variations represent an important source of genetic variation in mammal genomes, thus, they are commonly related to phenotypic expressions. In this work, ∼ 770,000 single nucleotide polymorphism genotypes...
3.
Bickhart D, Hou Y, Schroeder S, Alkan C, Cardone M, Matukumalli L, et al.
Genome Res
. 2012 Feb;
22(4):778-90.
PMID: 22300768
Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in or near segmental duplication regions are often intractable. Using a read depth approach based on next-generation...
4.
Hou Y, Liu G, Bickhart D, Matukumalli L, Li C, Song J, et al.
Funct Integr Genomics
. 2011 Sep;
12(1):81-92.
PMID: 21928070
Genomic structural variation is an important and abundant source of genetic and phenotypic variation. We previously reported an initial analysis of copy number variations (CNVs) in Angus cattle selected for...
5.
Cole J, Wiggans G, Ma L, Sonstegard T, Lawlor Jr T, Crooker B, et al.
BMC Genomics
. 2011 Aug;
12:408.
PMID: 21831322
Background: Genome-wide association analysis is a powerful tool for annotating phenotypic effects on the genome and knowledge of genes and chromosomal regions associated with dairy phenotypes is useful for genome...
6.
Hou Y, Liu G, Bickhart D, Cardone M, Wang K, Kim E, et al.
BMC Genomics
. 2011 Feb;
12:127.
PMID: 21345189
Background: Copy number variation (CNV) represents another important source of genetic variation complementary to single nucleotide polymorphism (SNP). High-density SNP array data have been routinely used to detect human CNVs,...
7.
Harhay G, Smith T, Alexander L, Haudenschild C, Keele J, Matukumalli L, et al.
Genome Biol
. 2010 Oct;
11(10):R102.
PMID: 20961407
Background: A comprehensive transcriptome survey, or gene atlas, provides information essential for a complete understanding of the genomic biology of an organism. We present an atlas of RNA abundance for...
8.
Liu G, Hou Y, Zhu B, Cardone M, Jiang L, Cellamare A, et al.
Genome Res
. 2010 Mar;
20(5):693-703.
PMID: 20212021
Genomic structural variation is an important and abundant source of genetic and phenotypic variation. Here, we describe the first systematic and genome-wide analysis of copy number variations (CNVs) in modern...
9.
Villa-Angulo R, Matukumalli L, Gill C, Choi J, Van Tassell C, Grefenstette J
BMC Genet
. 2009 Apr;
10:19.
PMID: 19393054
Background: The Bovine HapMap Consortium has generated assay panels to genotype ~30,000 single nucleotide polymorphisms (SNPs) from 501 animals sampled from 19 worldwide taurine and indicine breeds, plus two outgroup...
10.
Matukumalli L, Lawley C, Schnabel R, Taylor J, Allan M, Heaton M, et al.
PLoS One
. 2009 Apr;
4(4):e5350.
PMID: 19390634
The success of genome-wide association (GWA) studies for the detection of sequence variation affecting complex traits in human has spurred interest in the use of large-scale high-density single nucleotide polymorphism...