L S Jacobs
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Explore the profile of L S Jacobs including associated specialties, affiliations and a list of published articles.
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85
Citations
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Recent Articles
1.
Jacobs L, Douglas J
Hypertension
. 1996 Oct;
28(4):663-8.
PMID: 8843895
We investigated the ability of angiotensin II (Ang II) or the stable analogue [Sar1]-Ang II to increase intracellular and extracellular free arachidonic acid in primary cultures of rabbit proximal tubular...
2.
Jacobs L, Kester M
Am J Physiol
. 1993 Sep;
265(3 Pt 1):C740-7.
PMID: 8214030
The role of sphingolipids in mediating the action of platelet-derived growth factor (PDGF) has been investigated in the vascular smooth muscle-derived A7r5 cell line. L-Cycloserine (2 mM), an inhibitor of...
3.
Xie M, Jacobs L, Dubyak G
J Clin Invest
. 1991 Jul;
88(1):45-54.
PMID: 1905330
We have compared the abilities of extracellular ATP (acting via P2-purinergic receptors) and formylated peptides (FMLP) to stimulate both phospholipase D (PLD)-based signal transduction and primary granule (azurophilic) secretion in...
4.
Nussbaum C, Okawara S, Jacobs L
Neurosurgery
. 1991 Mar;
28(3):440-4.
PMID: 2011230
Two cases of lymphocytic hypophysitis are reported, in which hypothalamic involvement causing diabetes insipidus was a prominent clinical feature. In one case, a man had clinical and radiological evidence of...
5.
Jones S, Jacobs L
J Neurosci
. 1990 Jul;
10(7):2261-7.
PMID: 1695946
Dihydropyridines (DHPs) generally have little effect on whole-cell calcium currents of neurons, even at concentrations far higher than those effective on muscle. Either neuronal calcium currents are much less sensitive...
6.
Lorenson M, Cuccaro M, Jacobs L
Endocrinology
. 1990 May;
126(5):2671-8.
PMID: 1691704
The distribution of calcium in isolated bovine pituitary secretory granules was studied by atomic absorption. The total granule calcium (in 26 preparations) averaged 14.5 nmol/mg protein, or 21.2 +/- 1.6%...
7.
Jacobs L
Hawaii Med J
. 1989 Mar;
48(3):73-6.
PMID: 2732042
In Hawaii, crisis intervention services have become an increasingly pressing concern of the mental health and substance abuse systems. Since 1983, the Crisis Response System Project (CRSP) provided mobile crisis...
8.
Lorenson M, Jacobs L
Neuroendocrinology
. 1988 Apr;
47(4):358-64.
PMID: 3374761
Cysteamine (CySH) inhibits the immunodetectability and bioactivity of prolactin (PRL), and we have proposed that it may act by impeding the conversion from secretory granule hormone storage forms to releasable...
9.
Jacobs L, De Kock M, van der Merwe A
Burns Incl Therm Inj
. 1987 Apr;
13(2):154-8.
PMID: 3107763
It is well known that the marked hypermetabolic response of the human body to thermal injury requires aggressive nutritional support. In order to minimize catabolic conditions resulting in severe weight...
10.
Nelson T, Lorenson M, Jacobs L, Boyd 3rd A
Mol Cell Biochem
. 1987 Mar;
74(1):83-94.
PMID: 3587233
Calcium is necessary for secretion of pituitary hormones. Many of the biological effects of Ca2+ are mediated by the Ca2+-binding protein calmodulin (CaM), which interacts specifically with proteins regulated by...