L L von Moltke
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Explore the profile of L L von Moltke including associated specialties, affiliations and a list of published articles.
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108
Citations
2039
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Recent Articles
1.
von Moltke L, Greenblatt D, Romach M, Sellers E
Dialogues Clin Neurosci
. 2011 Oct;
3(3):181-90.
PMID: 22034128
The aged are an extremely heterogeneous population that is growing worldwide, included are healthy and agile individuals in their early sixties, as well as an increasing number of people over...
2.
Oleson L, von Moltke L, Greenblatt D, Court M
Xenobiotica
. 2010 Jan;
40(2):146-62.
PMID: 20082578
Single nucleotide polymorphisms in the 3'-untranslated region (3'UTR) of the human pregnane X receptor (PXR) gene might contribute to interindividual variability in cytochrome P450 3A (CYP3A) activity. Genotype-phenotype associations involving...
3.
Farkas D, Volak L, Harmatz J, von Moltke L, Court M, Greenblatt D
Clin Pharmacol Ther
. 2009 Feb;
85(6):644-50.
PMID: 19242403
The kinetic and dynamic interactions of 5 mg zolpidem and 50 mg trazodone with 500 mg clarithromycin (4 doses given over 32 h) were investigated in a 5-way double crossover...
4.
Cysneiros R, Farkas D, Harmatz J, von Moltke L, Greenblatt D
Clin Pharmacol Ther
. 2007 Apr;
82(1):54-62.
PMID: 17443132
The kinetic and dynamic interaction of caffeine and zolpidem was evaluated in a double-blind, single-dose, six-way crossover study of 7.5 mg zolpidem (Z) or placebo (P) combined with low-dose caffeine...
5.
Warrington J, Greenblatt D, von Moltke L
Xenobiotica
. 2004 Sep;
34(5):463-71.
PMID: 15370962
1. Triazolam (TRZ) has been used extensively in rat to evaluate its benzodiazepine agonist central nervous system effects. However, the pharmacokinetics of TRZ in the male rat are not well...
6.
Perloff M, von Moltke L, Greenblatt D
Xenobiotica
. 2004 Feb;
34(2):133-50.
PMID: 14985144
1. The consequences of extended exposure to the human immunodeficiency viral protease inhibitor ritonavir (RIT) on the expression and function of CYP3A isoforms in the liver and in enteric mucosal...
7.
Perloff M, von Moltke L, Greenblatt D
Xenobiotica
. 2003 May;
33(4):365-77.
PMID: 12745872
1. Although multiple cytochrome P450s (CYP) contribute to hepatic phase I metabolism, CYP3A is the principal subfamily present in human and mouse small intestine. 2. Differences in phase I metabolism...
8.
Krishnaswamy S, Duan S, von Moltke L, Greenblatt D, SUDMEIER J, Bachovchin W, et al.
Xenobiotica
. 2003 Mar;
33(2):169-80.
PMID: 12623759
1. The main purpose was to develop a high-performance liquid chromatography (HPLC)-based method to assay serotonin glucuronidation activity using liver microsomal fractions. Application of this method was then demonstrated by...
9.
Perloff M, von Moltke L, Marchand J, Greenblatt D
J Pharm Sci
. 2001 Dec;
90(11):1829-37.
PMID: 11745741
The present study characterized the response of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP1) to chronic ritonavir (RIT) exposure by assessing increases in P-gp and MRP1 protein expression and activity....
10.
Perloff M, von Moltke L, Stormer E, Shader R, Greenblatt D
Br J Pharmacol
. 2001 Dec;
134(8):1601-8.
PMID: 11739235
1. Chronic use of Saint John's wort (SJW) has been shown to lower the bioavailability for a variety of co-administered drugs including indinavir, cyclosporin, and digoxin. Decreases in intestinal absorption...