L Jakoi
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Explore the profile of L Jakoi including associated specialties, affiliations and a list of published articles.
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31
Citations
1513
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Recent Articles
1.
Freedman J, Chang J, Jakoi L, Nevins J
Oncogene
. 2009 Jun;
28(32):2873-81.
PMID: 19543322
Various studies have detailed the role of E2F proteins in both transcription activation and repression. Further study has shown that distinct promoter elements, but comprising the same E2F-recognition motif, confer...
2.
Gaubatz S, Lindeman G, Ishida S, Jakoi L, Nevins J, Livingston D, et al.
Mol Cell
. 2000 Oct;
6(3):729-35.
PMID: 11030352
E2F transcription factors are major regulators of cell proliferation. The diversity of the E2F family suggests that individual members perform distinct functions in cell cycle control. E2F4 and E2F5 constitute...
3.
Rempel R, Saenz-Robles M, Storms R, Morham S, Ishida S, Engel A, et al.
Mol Cell
. 2000 Sep;
6(2):293-306.
PMID: 10983977
We have generated mice deficient in E2F4 activity, the major form of E2F in many cell types. Analysis of newborn pups deficient in E2F4 revealed abnormalities in hematopoietic lineage development...
4.
Leone G, Nuckolls F, Ishida S, Adams M, Sears R, Jakoi L, et al.
Mol Cell Biol
. 2000 Apr;
20(10):3626-32.
PMID: 10779352
The tumor suppressor function of Rb is intimately related to its ability to interact with E2F and repress the transcription of E2F target genes. Here we describe a novel E2F...
5.
Leone G, DeGregori J, Jakoi L, Cook J, Nevins J
Proc Natl Acad Sci U S A
. 1999 Jun;
96(12):6626-31.
PMID: 10359762
A considerable body of evidence points to a role for both cyclin E/cyclin-dependent kinase (cdk)2 activity and E2F transcription activity in the induction of S phase. We show that overexpression...
6.
Leone G, DeGregori J, Yan Z, Jakoi L, Ishida S, Williams R, et al.
Genes Dev
. 1998 Jul;
12(14):2120-30.
PMID: 9679057
Previous work has demonstrated the important role of E2F transcription activity in the induction of S phase during the transition from quiescence to proliferation. In addition to the E2F-dependent activation...
7.
Kowalik T, DeGregori J, Leone G, Jakoi L, Nevins J
Cell Growth Differ
. 1998 Mar;
9(2):113-8.
PMID: 9486847
Previous work has demonstrated a role for E2F transcription factor activity in the regulation of cell growth during the G0/G1-S phase transition. Indeed, overexpression of E2F proteins, including the E2F1...
8.
Nevins J, Leone G, DeGregori J, Jakoi L
J Cell Physiol
. 1997 Nov;
173(2):233-6.
PMID: 9365528
No abstract available.
9.
DeGregori J, Leone G, Miron A, Jakoi L, Nevins J
Proc Natl Acad Sci U S A
. 1997 Jul;
94(14):7245-50.
PMID: 9207076
E2F transcription activity is composed of a family of heterodimers encoded by distinct genes. Through the overproduction of each of the five known E2F proteins in mammalian cells, we demonstrate...
10.
Leone G, DeGregori J, Sears R, Jakoi L, Nevins J
Nature
. 1997 May;
387(6631):422-6.
PMID: 9163430
Considerable evidence points to a role for G1 cyclin-dependent kinase (CDK) in allowing the accumulation of E2F transcription factor activity and induction of the S phase of the cell cycle....