L J Marnett
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Explore the profile of L J Marnett including associated specialties, affiliations and a list of published articles.
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251
Citations
5478
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Recent Articles
1.
Bluett R, Gamble-George J, Hermanson D, Hartley N, Marnett L, Patel S
Transl Psychiatry
. 2014 Jul;
4:e408.
PMID: 25004388
Stress is a major risk factor for the development of mood and anxiety disorders; elucidation of novel approaches to mitigate the deleterious effects of stress could have broad clinical applications....
2.
Rietjens I, Cohen S, Fukushima S, Gooderham N, Hecht S, Marnett L, et al.
Chem Res Toxicol
. 2014 May;
27(7):1092-103.
PMID: 24857813
The metabolic fate of a compound is determined by numerous factors including its chemical structure. Although the metabolic options for a variety of functional groups are well understood and can...
3.
Soares C, Boiani M, Marnett L, Bechara E
Free Radic Res
. 2013 Jun;
47(9):672-82.
PMID: 23758064
α-Aminocarbonyl metabolites (e.g., 5-aminolevulinic acid and aminoacetone) and the wide spectrum microbicide 1,4-diamino-2-butanone (DAB) have been shown to exhibit pro-oxidant properties. In vitro, these compounds undergo phosphate-catalyzed enolization at physiological...
4.
Yang Y, Yang H, Wang Z, Varadaraj K, Kumari S, Mergler S, et al.
Cell Signal
. 2012 Nov;
25(2):501-11.
PMID: 23142606
Cannabinoid receptor type 1 (CB1)-induced suppression of transient receptor potential vanilloid type 1 (TRPV1) activation provides a therapeutic option to reduce inflammation and pain in different animal disease models through...
5.
Adams T, Gavin C, McGowen M, Waddell W, Cohen S, Feron V, et al.
Food Chem Toxicol
. 2011 Jul;
49(10):2471-94.
PMID: 21726592
This publication is the thirteenth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a...
6.
Plastaras J, Marnett L
Curr Protoc Toxicol
. 2010 Oct;
Chapter 3:Unit3.2.
PMID: 20941700
Determining the levels of various DNA adducts has become an essential tool in understanding the toxicology of carcinogens. Direct measurement of DNA adduct levels, the true biologically effective dose of...
7.
Adams T, Gavin C, Taylor S, Waddell W, Cohen S, Feron V, et al.
Food Chem Toxicol
. 2008 Jul;
46(9):2935-67.
PMID: 18644420
This publication is the 12th in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a...
8.
Schnetz-Boutaud N, Chapeau M, Marnett L
Curr Protoc Nucleic Acid Chem
. 2008 Apr;
Chapter 1:Unit1.2.
PMID: 18428817
Adducts formed between electrophiles and nucleic acid bases are believed to play a key role in chemically induced mutations and cancer. M(1)G-dR is an endogenous exocyclic DNA adduct formed by...
9.
Adams T, McGowen M, Williams M, Cohen S, Feron V, Goodman J, et al.
Food Chem Toxicol
. 2006 Oct;
45(2):171-201.
PMID: 17046133
This publication is the 11th in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a...
10.
Adams T, Cohen S, DOULL J, Feron V, Goodman J, Marnett L, et al.
Food Chem Toxicol
. 2005 Jun;
43(8):1241-71.
PMID: 15950816
This publication is the ninth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a...