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L J Macala

Explore the profile of L J Macala including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 369
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11.
Bonafede D, Macala L, Constantine-Paton M, Yu R
Lipids . 1989 Aug; 24(8):680-4. PMID: 2685488
Bovine buttermilk contains a unique ganglioside, 9-O-acetyl-GD3. In order to isolate large quantities of this ganglioside, a simplified isolation scheme which consists of several ion-exchange and silica gel column chromatographic...
12.
Yu R, Macala L, Farooq M, Sbaschnig-Agler M, Norton W, Ledeen R
J Neurosci Res . 1989 Jun; 23(2):136-41. PMID: 2754761
We have examined the ganglioside composition of 30-day and 60-day postnatal rat oligodendroglia, adult bovine oligodendroglia, gray matter, white matter, and myelin and also the total lipid composition of the...
13.
Yu R, Macala L, Taki T, Weinfield H, Yu F
J Neurochem . 1988 Jun; 50(6):1825-9. PMID: 3131485
Developmental changes in ganglioside composition and biosynthesis was studied in rat brain between embryonic day (E) 14 and birth. In E14 brains, GM3 and GD3 were predominant. At E16, "b"...
14.
Ariga T, Macala L, Saito M, Margolis R, Greene L, Margolis R, et al.
Biochemistry . 1988 Jan; 27(1):52-8. PMID: 3349045
We have studied the lipid composition of PC12 pheochromocytoma cells cultured in the presence and absence of nerve growth factor (NGF). Neutral and acidic lipid fractions were isolated by column...
15.
Yu R, Holley J, Macala L, Spencer D
Yale J Biol Med . 1987 Mar; 60(2):107-17. PMID: 3554791
To understand better the molecular and cellular events associated with status epilepticus, a multifaceted analysis has begun on hippocampal tissues therapeutically removed from patients with temporal lobe epilepsy. In this...
16.
Saito M, Macala L, Roth G, Bornstein M, Yu R
Exp Neurol . 1986 Jun; 92(3):752-6. PMID: 3709746
To examine the effect of antiglycolipid antibodies on demyelination, myelinated cultures of embryonic mouse spinal cords were treated by antigalactocerebroside (anti-GC), anti-GM1; and anti-GM4 antisera, and the lipid composition of...
17.
Carubia J, Yu R, Macala L, Kirkwood J, VARGA J
Biochem Biophys Res Commun . 1984 Apr; 120(2):500-4. PMID: 6732768
The major ganglioside component isolated from diploid human melanocytes is sialosyllactosylceramide (GM3 86-91% of total sialic acid). The corresponding disialo derivative (GD3) is found as a minor component (2-6% of...
18.
Yu R, Itoh T, Yohe H, Macala L
Brain Res . 1983 Sep; 275(1):47-52. PMID: 6414648
No abstract available.
19.
Macala L, Yu R, Ando S
J Lipid Res . 1983 Sep; 24(9):1243-50. PMID: 6631248
We have devised a high performance thin-layer chromatography (HPTLC) densitometry method to resolve the major lipid classes of brain tissue. We used DEAE-Sephadex column chromatography to separate the total lipid...
20.
Yohe H, Macala L, Yu R
J Biol Chem . 1982 Jan; 257(1):249-52. PMID: 7053368
A sialyltransferase activity which catalyzes the synthesis of the tetrasialoganglioside GQ1b (N-acetylneuraminyl-N-acetylneuraminylgalactosyl-N-acetylgalactosaminyl [N-acetylneuraminyl-N-acetylneuraminyl]-galactosylglucosylceramide) from added trisialoganglioside GT1b (N-=acetylneuraminylgalactosyl-N-acetylgalactosaminyl [N-acetylneuraminyl-N-acetylneuraminyl]galactosylglucosylceramide) and CMP-N-acetyl[4-14C]neuraminic acid has been demonstrated using a membrane fraction of...