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H C Yohe

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Articles 32
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Recent Articles
1.
Yohe H, Kitzmiller T, Bement W, Dwyer B, Sinclair J
Inflammopharmacology . 2006 Sep; 14(3-4):170-5. PMID: 16983496
Integral components of mammalian cell membranes, glycosphingolipids (GSL) reside in specialized plasma membrane microdomains critical for cell signaling. N-alkylated nojirimycins are compounds developed for GSL substrate deprivation therapy, blocking GSL...
2.
Yohe H, Wallace P, Berenson C, Ye S, Reinhold B, Reinhold V
Glycobiology . 2001 Oct; 11(10):831-41. PMID: 11588159
Sialoglycosphingolipids (gangliosides) are membrane components of eukaryotic cells that modulate cell signal transduction events. Discrepancies exist in the published descriptions of the gangliosides present in the human peripheral monocyte/macrophage. Macrophages...
3.
Berenson C, Rasp R, Gau J, Ryan J, Yohe H
J Leukoc Biol . 2001 Jun; 69(6):969-76. PMID: 11404384
Endotoxin-responsive (C3H/HeN) and -hyporesponsive (C3H/HeJ) murine B lymphocytes purified by adherence to anti-immunoglobulin ("antibody panning") possess identical gangliosides but different ganglioside surface accessibilities. We investigated the distribution and surface accessibility...
4.
Ecsedy J, Holthaus K, Yohe H, Seyfried T
J Neurochem . 1999 Jul; 73(1):254-9. PMID: 10386978
Ganglioside sialic acid content was examined in the U87-MG human glioma grown as cultured cells and as a xenograft in severe combined immunodeficiency (SCID) mice. The cultured cells and the...
5.
Ecsedy J, Yohe H, Bergeron A, Seyfried T
J Lipid Res . 1998 Nov; 39(11):2218-27. PMID: 9799808
A procedure was developed to analyze glycosphingolipids (GSLs) in tumor-infiltrating macrophages (TIMs). The procedure entailed dissociating tumors into single cell suspensions with a concurrent metabolic labeling of GSLs using [14C]galactose....
6.
Seyfried T, Ecsedy J, Griffin M, Yohe H
Mol Chem Neuropathol . 1998 Mar; 33(1):27-37. PMID: 9493174
The content and composition of gangliosides were examined in an experimental mouse brain tumor, EPEN, that was grown subcutaneously in the flank of the syngeneic C57BL/6J (B6) host and in...
7.
Yohe H, Ye S, Reinhold B, Reinhold V
Glycobiology . 1998 Feb; 7(8):1215-27. PMID: 9455923
Sialoglycosphingolipids (gangliosides) have been increasingly implicated as regulators of membrane signaling events. Macrophage ganglioside patterns dramatically increase in complexity when murine peritoneal macrophages are stimulated in vivo with the appearance...
8.
Ecsedy J, Manfredi M, Yohe H, Seyfried T
Cancer Res . 1997 Apr; 57(8):1580-3. PMID: 9108463
The genes for cytidine monophospho-N-acetylneuraminic acid hydroxylase (NeuAc-H) and beta-1,4-N-acetylgalactosaminyl transferase (GalNAc-T) were examined using reverse transcription-PCR in two experimental mouse brain tumors, EPEN and CT-2A. NeuAc-H is required for...
9.
Seyfried T, Ecsedy J, Bai H, Yohe H
J Neurochem . 1996 May; 66(5):2026-33. PMID: 8780032
Previous studies showed that levels of some glycosphingolipids (GSLs) expressed in solid brain tumors grown in vivo were reduced or undetectable in cultured cells prepared from the tumors. This phenomenon...
10.
Macala L, Yohe H
Glycobiology . 1995 Feb; 5(1):67-75. PMID: 7772869
Gangliosides are implicated in cell signal transduction. Prior to investigating this phenomenon in macrophages, the in situ accessibility of gangliosides to macromolecules was assessed for peritoneal macrophages isolated from normal...