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L Gotlib

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Articles 16
Citations 235
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Droeser R, Kaneva P, Cheng V, Lam L, Benjamin E, Matsushima K, et al.
Can J Surg . 2022 Apr; 61(4 Suppl 1):S94-S174. PMID: 35488393
No abstract available.
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Stahlhut M, Li Y, Condra J, Fu J, Gotlib L, Graham D, et al.
Protein Expr Purif . 1994 Dec; 5(6):614-21. PMID: 7532052
Wild-type and several mutant forms of recombinant human immunodeficiency virus type-1 reverse transcriptase were overexpressed as either the p66 or the p51 subunit in a protease-deficient strain of Escherichia coli....
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Byrnes V, Emini E, Schleif W, Condra J, Schneider C, Long W, et al.
Antimicrob Agents Chemother . 1994 Jun; 38(6):1404-7. PMID: 7522428
To evaluate the potential that multiply resistant human immunodeficiency virus type 1 variants may arise during combination nucleoside and nonnucleoside reverse transcriptase inhibitor therapy, we constructed a series of mutant...
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Sardana V, Schlabach A, Graham P, Bush B, Condra J, Culberson J, et al.
Biochemistry . 1994 Mar; 33(8):2004-10. PMID: 8117657
The human immunodeficiency virus type 1 (HIV-1) protease is a homodimeric aspartyl endopeptidase that is required for virus replication. A number of specific, active-site inhibitors for this enzyme have been...
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Emini E, Graham D, Gotlib L, Condra J, Byrnes V, Schleif W
Nature . 1993 Aug; 364(6439):679. PMID: 7689173
No abstract available.
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Carroll S, Olsen D, Bennett C, Gotlib L, Graham D, Condra J, et al.
J Biol Chem . 1993 Jan; 268(1):276-81. PMID: 7677997
The inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by pyridinone compounds has been investigated using as templates synthetic RNA with sequences based on the HIV-1 genome sequence....
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Sardana V, Emini E, Gotlib L, Graham D, Lineberger D, Long W, et al.
J Biol Chem . 1992 Sep; 267(25):17526-30. PMID: 1381350
Several novel, structurally distinct classes of specific human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) nonnucleoside inhibitors have been described recently. These include the pyridinone derivatives L-697,639, L-697,661, and...
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Condra J, Emini E, Gotlib L, Graham D, Schlabach A, Wolfgang J, et al.
Antimicrob Agents Chemother . 1992 Jul; 36(7):1441-6. PMID: 1380789
The reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) is potently inhibited by a structurally diverse group of nonnucleoside compounds. These include pyridinone derivatives, tetrahydroimadazo[4,5,1-j,k][1,4]-benzodiazepin-2(1H)-one and -thione, and...
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GARBER E, Chute H, Condra J, Gotlib L, Colonno R, Smith R
Virology . 1991 Feb; 180(2):754-62. PMID: 1989389
The cDNA encoding the murine Mx1 protein, a mediator of resistance to influenza virus, was inserted into a replication-competent avian retroviral vector in either the sense (referred to as Mx+)...