Kyle R Kays
Overview
Explore the profile of Kyle R Kays including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
379
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Recent Articles
1.
LaSalle T, Gonye A, Freeman S, Kaplonek P, Gushterova I, Kays K, et al.
Cell Rep Med
. 2022 Oct;
3(10):100779.
PMID: 36208629
Mechanisms of neutrophil involvement in severe coronavirus disease 2019 (COVID-19) remain incompletely understood. Here, we collect longitudinal blood samples from 306 hospitalized COVID-19 patients and 86 controls and perform bulk...
2.
Wang C, Li Y, Kaplonek P, Gentili M, Fischinger S, Bowman K, et al.
mBio
. 2022 Jun;
13(4):e0157722.
PMID: 35762593
Persistent SARS-CoV-2 replication and systemic dissemination are linked to increased COVID-19 disease severity and mortality. However, the precise immune profiles that track with enhanced viral clearance, particularly from systemic RNAemia,...
3.
Leisman D, Mehta A, Thompson B, Charland N, Gonye A, Gushterova I, et al.
Am J Respir Crit Care Med
. 2021 Dec;
205(5):507-519.
PMID: 34878969
Alveolar and endothelial injury may be differentially associated with coronavirus disease (COVID-19) severity over time. To describe alveolar and endothelial injury dynamics and associations with COVID-19 severity, cardiorenovascular injury, and...
4.
LaSalle T, Gonye A, Freeman S, Kaplonek P, Gushterova I, Kays K, et al.
bioRxiv
. 2021 Oct;
PMID: 34642692
Multiple studies have identified an association between neutrophils and COVID-19 disease severity; however, the mechanistic basis of this association remains incompletely understood. Here we collected 781 longitudinal blood samples from...
5.
Fenyves B, Mehta A, Kays K, Beakes C, Margolin J, Goldberg M, et al.
Am J Hematol
. 2021 Oct;
96(12):E468-E471.
PMID: 34622480
No abstract available.
6.
Leisman D, Mehta A, Li Y, Kays K, Li J, Filbin M, et al.
Br J Anaesth
. 2021 Aug;
127(4):e146-e148.
PMID: 34399981
No abstract available.
7.
Fenyves B, Mehta A, Kays K, Goldberg M, Hacohen N, Filbin M
medRxiv
. 2021 Jul;
PMID: 34282425
Coagulopathy and thromboembolism are known complications of SARS-CoV-2 infection. The mechanisms of COVID-19-associated hematologic complications involve endothelial cell and platelet dysfunction and have been intensively studied. We leveraged a prospectively...
8.
Li Y, Schneider A, Mehta A, Sade-Feldman M, Kays K, Gentili M, et al.
J Clin Invest
. 2021 Jul;
131(13).
PMID: 34196300
BACKGROUNDSARS-CoV-2 plasma viremia has been associated with severe disease and death in COVID-19 in small-scale cohort studies. The mechanisms behind this association remain elusive.METHODSWe evaluated the relationship between SARS-CoV-2 viremia,...
9.
Reyes M, Filbin M, Bhattacharyya R, Sonny A, Mehta A, Billman K, et al.
Sci Transl Med
. 2021 Jun;
13(598).
PMID: 34103408
Bacterial sepsis and severe COVID-19 share similar clinical manifestations and are both associated with dysregulation of the myeloid cell compartment. We previously reported an expanded CD14 monocyte state, MS1, in...
10.
Filbin M, Mehta A, Schneider A, Kays K, Guess J, Gentili M, et al.
Cell Rep Med
. 2021 May;
2(5):100287.
PMID: 33969320
Mechanisms underlying severe coronavirus disease 2019 (COVID-19) disease remain poorly understood. We analyze several thousand plasma proteins longitudinally in 306 COVID-19 patients and 78 symptomatic controls, uncovering immune and non-immune...