Kurt Drickamer
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Explore the profile of Kurt Drickamer including associated specialties, affiliations and a list of published articles.
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65
Citations
2180
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Recent Articles
1.
Benjamin S, Taylor M, Drickamer K
Glycobiology
. 2025 Mar;
35(4).
PMID: 40037288
An increasing number of clinical applications employ oligosaccharides as tags to direct therapeutic proteins and RNA molecules to specific target cells. Current applications are focused on endocytic receptors that result...
2.
Benjamin S, Jegouzo S, Lieng C, Daniels C, Coispeau M, Lau R, et al.
J Biol Chem
. 2024 Oct;
300(11):107869.
PMID: 39384043
A human lectin array has been developed to probe the interactions of innate immune receptors with pathogenic and commensal microorganisms. Following the successful introduction of a lectin array containing all...
3.
Liu Y, Drickamer K, Taylor M
Glycobiology
. 2024 Oct;
34(12).
PMID: 39361919
The sugar-binding receptor mincle stimulates macrophages when it encounters surface glycans on pathogens, such as trehalose dimycolate glycolipid in the outer membrane of mycobacteria. Binding of oligosaccharide ligands to the...
4.
Liu Y, Kim J, Feinberg H, Cull N, Weis W, Taylor M, et al.
Glycobiology
. 2024 Oct;
34(12).
PMID: 39361900
The sugar-binding receptors dectin-2 and blood dendritic cell antigen 2 (BDCA-2) bind oligosaccharide ligands through extracellular carbohydrate-recognition domains (CRDs) and initiate intracellular signaling through Fc receptor γ adapters (FcRγ). Dectin-2...
5.
Feinberg H, Jegouzo S, Lasanajak Y, Smith D, Drickamer K, Weis W, et al.
J Biol Chem
. 2021 Feb;
296:100368.
PMID: 33545173
The human mannose receptor expressed on macrophages and hepatic endothelial cells scavenges released lysosomal enzymes, glycopeptide fragments of collagen, and pathogenic microorganisms and thus reduces damage following tissue injury. The...
6.
Jegouzo S, Nelson C, Hardwick T, Wong S, Lau N, Neoh G, et al.
J Biol Chem
. 2020 Feb;
295(14):4541-4555.
PMID: 32094229
Many members of the C-type lectin family of glycan-binding receptors have been ascribed roles in the recognition of microorganisms and serve as key receptors in the innate immune response to...
7.
Jegouzo S, Feinberg H, Morrison A, Holder A, May A, Huang Z, et al.
J Biol Chem
. 2019 Sep;
294(41):14845-14859.
PMID: 31488546
CD23, the low-affinity IgE receptor found on B lymphocytes and other cells, contains a C-terminal lectin-like domain that resembles C-type carbohydrate-recognition domains (CRDs) found in many glycan-binding receptors. In most...
8.
Taylor M, Drickamer K
FEBS J
. 2019 Jan;
286(10):1800-1814.
PMID: 30657247
Mammalian glycan-binding receptors, sometimes known as lectins, interact with glycans, the oligosaccharide portions of endogenous mammalian glycoproteins and glycolipids as well as sugars on the surfaces of microbes. These receptors...
9.
Taylor M, Snelling T, Smith D, Drickamer K
Glycobiology
. 2018 Dec;
29(4):332-345.
PMID: 30590594
The murine CLEC4f gene encodes the Kupffer cell receptor, a galactose-binding receptor containing a C-type carbohydrate-recognition domain. Orthologs have been identified in nearly 100 species. The receptors from rat and...
10.
Kim J, Budzak J, Liu Y, Jegouzo S, Drickamer K, Taylor M
Glycobiology
. 2018 May;
28(8):592-600.
PMID: 29796630
Blood dendritic cell antigen 2 (BDCA-2) is a C-type lectin found on the surface of plasmacytoid dendritic cells. It functions as a glycan-binding receptor that downregulates the production of type...