Andrew J Fadden
Overview
Explore the profile of Andrew J Fadden including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
252
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0
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Recent Articles
1.
Jegouzo S, Harding E, Acton O, Rex M, Fadden A, Taylor M, et al.
Glycobiology
. 2014 Jul;
24(12):1291-300.
PMID: 25028392
Trehalose dimycolate, an unusual glycolipid in the outer membrane of Mycobacterium tuberculosis, stimulates macrophages by binding to the macrophage receptor mincle. This stimulation plays an important role both in infection...
2.
Fadden A, Schalbetter S, Bowles M, Harris R, Lally J, Carr A, et al.
Nucleic Acids Res
. 2013 Aug;
41(21):9741-52.
PMID: 23982516
The MUS81-EME1 endonuclease maintains metazoan genomic integrity by cleaving branched DNA structures that arise during the resolution of recombination intermediates. In humans, MUS81 also forms a poorly characterized complex with...
3.
Bowles M, Lally J, Fadden A, Mouilleron S, Hammonds T, McDonald N
Nucleic Acids Res
. 2012 Mar;
40(13):e101.
PMID: 22457069
The structure-specific endonuclease activity of the human XPF-ERCC1 complex is essential for a number of DNA processing mechanisms that help to maintain genomic integrity. XPF-ERCC1 cleaves DNA structures such as...
4.
Boeda B, Briggs D, Higgins T, Garvalov B, Fadden A, McDonald N, et al.
Mol Cell
. 2007 Dec;
28(6):1071-82.
PMID: 18158903
The intracellular targeting of Ena/VASP family members is achieved via the interaction of their EVH1 domain with FPPPP sequence motifs found in a variety of cytoskeletal proteins, including lamellipodin, vinculin,...
5.
Houzelstein D, Goncalves I, Fadden A, Sidhu S, Cooper D, Drickamer K, et al.
Mol Biol Evol
. 2004 Feb;
21(7):1177-87.
PMID: 14963092
Galectins form a family of structurally related carbohydrate binding proteins (lectins) that have been identified in a large variety of metazoan phyla. They are involved in many biological processes such...
6.
Fadden A, Holt O, Drickamer K
Glycobiology
. 2003 Apr;
13(7):529-37.
PMID: 12672702
The Kupffer cell receptor for glycoproteins has been reported to have a role in clearance of galactose- and fucose-terminated glycoproteins from circulation. Although the gene and a cDNA encoding the...
7.
Drickamer K, Fadden A
Biochem Soc Symp
. 2003 Mar;
(69):59-72.
PMID: 12655774
Many biological effects of complex carbohydrates are mediated by lectins that contain discrete carbohydrate-recognition domains. At least seven structurally distinct families of carbohydrate-recognition domains are found in lectins that are...