Kunihiko Nishino
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Explore the profile of Kunihiko Nishino including associated specialties, affiliations and a list of published articles.
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97
Citations
2933
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Recent Articles
1.
Yamasaki S, Koga N, Nakashima R, Hayashi-Nishino M, Nishino K
Biol Pharm Bull
. 2025 Mar;
48(3):230-233.
PMID: 40024693
The rapid emergence of drug-resistant microbes has recently become a major concern in the medical field. In Pseudomonas aeruginosa, one of the most important mechanisms underlying antibiotic resistance is MexAB-OprM...
2.
Ikebe M, Aoki K, Hayashi-Nishino M, Furusawa C, Nishino K
Front Microbiol
. 2024 Oct;
15:1450804.
PMID: 39364166
Although it is well known that the morphology of Gram-negative rods changes on exposure to antibiotics, the morphology of antibiotic-resistant bacteria in the absence of antibiotics has not been widely...
3.
Taguchi A, Nakashima R, Nishino K
J Mol Biol
. 2024 Jul;
436(18):168708.
PMID: 39009072
Nucleoside triphosphates are indispensable in numerous biological processes, with enzymes involved in their biogenesis playing pivotal roles in cell proliferation. Pyruvate kinase (PYK), commonly regarded as the terminal glycolytic enzyme...
4.
Giraud E, Baucheron S, Foubert I, Doublet B, Nishino K, Cloeckaert A
Front Microbiol
. 2024 Feb;
15:1338261.
PMID: 38410385
Bile represses serovar Typhimurium (. Typhimurium) intestinal cell invasion, but it remains unclear which bile components and mechanisms are implicated. Previous studies reported that bile inhibits the RamR binding to...
5.
Matsumoto Y, Yamasaki S, Hayama K, Iino R, Noji H, Yamaguchi A, et al.
Proc Jpn Acad Ser B Phys Biol Sci
. 2024 Jan;
100(1):57-67.
PMID: 38199247
Changes in expression levels of drug efflux pump genes, mexB and mexY, and porin gene oprD in Pseudomonas aeruginosa were investigated in this study. Fifty-five multidrug-resistant P. aeruginosa (MDRP) strains...
6.
Yamasaki S, Zwama M, Yoneda T, Hayashi-Nishino M, Nishino K
Microbiology (Reading)
. 2023 Jun;
169(6).
PMID: 37319001
No abstract available.
7.
Taguchi A, Nakashima R, Nishino K
J Biol Chem
. 2023 Jun;
299(7):104892.
PMID: 37286036
Glycolysis is the primary metabolic pathway in the strictly fermentative Streptococcus pneumoniae, which is a major human pathogen associated with antibiotic resistance. Pyruvate kinase (PYK) is the last enzyme in...
8.
Yamasaki S, Yoneda T, Ikawa S, Hayashi-Nishino M, Nishino K
Front Microbiol
. 2023 Mar;
14:954304.
PMID: 36896427
Fatty acids salts exert bactericidal and bacteriostatic effects that inhibit bacterial growth and survival. However, bacteria can overcome these effects and adapt to their environment. Bacterial efflux systems are associated...
9.
Satoh A, Hayashi-Nishino M, Nishino K
Methods Mol Biol
. 2022 Dec;
2557:235-246.
PMID: 36512219
The Golgi apparatus is an organelle that mediates modifications, sorting, and transport of proteins and lipids. Golgins are a group of proteins with coiled-coil structures that localize to the Golgi...
10.
Yamasaki S, Koga N, Zwama M, Sakurai K, Nakashima R, Yamaguchi A, et al.
Antimicrob Agents Chemother
. 2022 Oct;
66(11):e0067222.
PMID: 36300935
The multidrug efflux transporters MexB and MexY in Pseudomonas aeruginosa and AcrB in Escherichia coli contribute to these organisms' multidrug resistance. Efflux pump inhibitor (EPI) ABI-PP inhibits MexB and AcrB,...