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Kumar Selvarajoo

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Articles 56
Citations 524
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Recent Articles
1.
Elhalis H, Helmy M, Ho S, Leow S, Liu Y, Selvarajoo K, et al.
Biotechnol Notes . 2024 Oct; 5:13-22. PMID: 39416691
Chitin is a major component of various wastes such as crustacean shells, filamentous fungi, and insects. Recently, food-safe biological and chemical processes converting chitin to glucosamine have been developed. Here,...
2.
Yeo H, Vijay V, Selvarajoo K
BMC Biol . 2024 Oct; 22(1):235. PMID: 39402553
Background: The transition from explanative modeling of fitted data to the predictive modeling of unseen data for systems biology endeavors necessitates the effective recovery of reaction parameters. Yet, the relative...
3.
Khanijou J, Hee Y, Scipion C, Chen X, Selvarajoo K
NPJ Syst Biol Appl . 2024 Oct; 10(1):109. PMID: 39353984
Engineered microorganisms have emerged as viable alternatives for limonene production. However, issues such as low enzyme abundance or activities, and regulatory feedback/forward inhibition may reduce yields. To understand the underlying...
4.
Pabis K, Barardo D, Gruber J, Sirbu O, Malavolta M, Selvarajoo K, et al.
Ageing Res Rev . 2024 Sep; 101:102512. PMID: 39332712
Although lifespan extension remains the gold standard for assessing interventions proposed to impact the biology of aging, there are important limitations to this approach. Our reanalysis of lifespan studies from...
5.
Rashid M, Selvarajoo K
Brief Bioinform . 2024 Jun; 25(4). PMID: 38904542
The inherent heterogeneity of cancer contributes to highly variable responses to any anticancer treatments. This underscores the need to first identify precise biomarkers through complex multi-omics datasets that are now...
6.
Selvarajoo K, Maurer-Stroh S
Brief Bioinform . 2024 May; 25(3). PMID: 38711370
Across many scientific disciplines, the development of computational models and algorithms for generating artificial or synthetic data is gaining momentum. In biology, there is a great opportunity to explore this...
7.
Pabis K, Barardo D, Sirbu O, Selvarajoo K, Gruber J, Kennedy B
Elife . 2024 Apr; 12. PMID: 38567944
Aging and senescence are characterized by pervasive transcriptional dysfunction, including increased expression of transposons and introns. Our aim was to elucidate mechanisms behind this increased expression. Most transposons are found...
8.
Helmy M, Elhalis H, Rashid M, Selvarajoo K
Curr Opin Biotechnol . 2024 Mar; 87:103115. PMID: 38547588
With the continuous increment in global population growth, compounded by post-pandemic food security challenges due to labor shortages, effects of climate change, political conflicts, limited land for agriculture, and carbon...
9.
Khanijou J, Hee Y, Selvarajoo K
Methods Mol Biol . 2023 Dec; 2745:3-19. PMID: 38060176
Living cells display dynamic and complex behaviors. To understand their response and to infer novel insights not possible with traditional reductionist approaches, over the last few decades various computational modelling...
10.
Selvarajoo K, Giuliani A
Biomolecules . 2023 Jul; 13(7). PMID: 37509116
For many years, there has been general interest in developing virtual cells or digital twin models [...].