Kostya I Panov
Overview
Explore the profile of Kostya I Panov including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
365
Followers
0
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Recent Articles
1.
Albert B, Leger-Silvestre I, Normand C, Ostermaier M, Perez-Fernandez J, Panov K, et al.
J Cell Biol
. 2011 Jan;
192(2):277-93.
PMID: 21263028
RNA polymerase I (Pol I) produces large ribosomal RNAs (rRNAs). In this study, we show that the Rpa49 and Rpa34 Pol I subunits, which do not have counterparts in Pol...
2.
McMahon M, Ayllon V, Panov K, OConnor R
J Biol Chem
. 2010 Apr;
285(24):18309-18.
PMID: 20392698
Insulin-like growth factor-I (IGF-I) signaling is strongly associated with cell growth and regulates the rate of synthesis of the rRNA precursor, the first and the key stage of ribosome biogenesis....
3.
Birch J, Tan B, Panov K, Panova T, Andersen J, Owen-Hughes T, et al.
EMBO J
. 2009 Feb;
28(7):854-65.
PMID: 19214185
Efficient transcription elongation from a chromatin template requires RNA polymerases (Pols) to negotiate nucleosomes. Our biochemical analyses demonstrate that RNA Pol I can transcribe through nucleosome templates and that this...
4.
Bracken C, Wall S, Barre B, Panov K, Ajuh P, Perkins N
Cancer Res
. 2008 Sep;
68(18):7621-8.
PMID: 18794151
Cyclin D1 expression represents one of the key mitogen-regulated events during the G(1) phase of the cell cycle, whereas Cyclin D1 overexpression is frequently associated with human malignancy. Here, we...
5.
Panova T, Panov K, Russell J, Zomerdijk J
Mol Cell Biol
. 2006 Aug;
26(16):5957-68.
PMID: 16880508
Mammalian RNA polymerase I (Pol I) complexes contain a number of associated factors, some with undefined regulatory roles in transcription. We demonstrate that casein kinase 2 (CK2) in human cells...
6.
Panov K, Friedrich J, Russell J, Zomerdijk J
EMBO J
. 2006 Jul;
25(14):3310-22.
PMID: 16858408
Ribosomal RNA gene transcription by RNA polymerase I (Pol I) is the driving force behind ribosome biogenesis, vital to cell growth and proliferation. The key activator of Pol I transcription,...
7.
Panov K, Panova T, Gadal O, Nishiyama K, Saito T, Russell J, et al.
Mol Cell Biol
. 2006 Jul;
26(14):5436-48.
PMID: 16809778
Eukaryotic RNA polymerases are large complexes, 12 subunits of which are structurally or functionally homologous across the three polymerase classes. Each class has a set of specific subunits, likely targets...
8.
Friedrich J, Panov K, cabart P, Russell J, Zomerdijk J
J Biol Chem
. 2005 Jun;
280(33):29551-8.
PMID: 15970593
Knowledge of the role of components of the RNA polymerase I transcription machinery is paramount to understanding regulation of rDNA expression. We describe key findings for the roles of essential...