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Jorge Perez-Fernandez

Explore the profile of Jorge Perez-Fernandez including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 600
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Recent Articles
1.
Fernandez-Fernandez J, Martin-Villanueva S, Perez-Fernandez J, de la Cruz J
J Mol Biol . 2023 Oct; 435(24):168321. PMID: 37865285
Ribosomal proteins have important roles in maintaining the structure and function of mature ribosomes, but they also drive crucial rearrangement reactions during ribosome biogenesis. The contribution of most, but not...
2.
Braun C, Knuppel R, Perez-Fernandez J, Ferreira-Cerca S
Methods Mol Biol . 2022 Jul; 2533:199-213. PMID: 35796990
RNA molecules and their expression dynamics play essential roles in the establishment of complex cellular phenotypes and/or in the rapid cellular adaption to environmental changes. Accordingly, analyzing RNA expression remains...
3.
Gutierrez-Santiago F, Cintas-Galan M, Martin-Exposito M, Del Carmen Mota-Trujillo M, Cobo-Huesa C, Perez-Fernandez J, et al.
Genes (Basel) . 2022 May; 13(5). PMID: 35627133
Bud27 is a prefoldin-like, a member of the family of ATP-independent molecular chaperones that associates with RNA polymerases I, II, and III in . Bud27 and its human ortholog URI...
4.
Dielforder T, Braun C, Holzgen F, Li S, Thiele M, Huber M, et al.
Noncoding RNA . 2022 Jan; 8(1). PMID: 35076539
The synthesis of ribosomes involves the correct folding of the pre-ribosomal RNA within pre-ribosomal particles. The first ribosomal precursor or small subunit processome assembles stepwise on the nascent transcript of...
5.
Lesage E, Perez-Fernandez J, Queille S, Dez C, Gadal O, Kwapisz M
Noncoding RNA . 2021 Jul; 7(3). PMID: 34287362
Pervasive transcription is widespread in eukaryotes, generating large families of non-coding RNAs. Such pervasive transcription is a key player in the regulatory pathways controlling chromatin state and gene expression. Here,...
6.
Braun C, Hackert P, Schmid C, Bohnsack M, Bohnsack K, Perez-Fernandez J
Nucleic Acids Res . 2019 Nov; 48(1):405-420. PMID: 31745560
More than 200 assembly factors (AFs) are required for the production of ribosomes in yeast. The stepwise association and dissociation of these AFs with the pre-ribosomal subunits occurs in a...
7.
Boissier F, Schmidt C, Linnemann J, Fribourg S, Perez-Fernandez J
Sci Rep . 2017 Jun; 7(1):3169. PMID: 28600509
The SSU processome constitutes a large ribonucleoprotein complex involved in the early steps of ribosome biogenesis. UTP-B is one of the first multi-subunit protein complexes that associates with the pre-ribosomal...
8.
Bruckmann A, Linnemann J, Perez-Fernandez J
Methods Mol Biol . 2016 Sep; 1455:213-23. PMID: 27576721
The native template of all eukaryotic nuclear RNA polymerases is chromatin. To understand how transcription occurs in vivo, it is important to define the chromatin environment of transcribing RNA Pols....
9.
Poll G, Li S, Ohmayer U, Hierlmeier T, Milkereit P, Perez-Fernandez J
PLoS One . 2014 Dec; 9(12):e114898. PMID: 25501974
Eukaryotic ribosome biogenesis is a multistep process involving more than 150 biogenesis factors, which interact transiently with pre-ribosomal particles to promote their maturation. Some of these auxiliary proteins have been...
10.
Merkl P, Perez-Fernandez J, Pilsl M, Reiter A, Williams L, Gerber J, et al.
Mol Cell Biol . 2014 Aug; 34(20):3817-27. PMID: 25092870
Different models have been proposed explaining how eukaryotic gene transcription is terminated. Recently, Nsi1, a factor involved in silencing of ribosomal DNA (rDNA), was shown to be required for efficient...