Konstantin V Pavlov
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Explore the profile of Konstantin V Pavlov including associated specialties, affiliations and a list of published articles.
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20
Citations
383
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Recent Articles
1.
Volynsky P, Urban A, Pavlov K, Bershatsky Y, Bocharova O, Kryuchkova A, et al.
Int J Mol Sci
. 2025 Jan;
26(2).
PMID: 39859269
Alzheimer's disease (AD) pathogenesis is correlated with the membrane content of various lipid species, including cholesterol, whose interactions with amyloid precursor protein (APP) have been extensively explored. Amyloid-β peptides triggering...
2.
Bershatsky Y, Kuznetsov A, Idiatullina A, Bocharova O, Dolotova S, Gavrilenkova A, et al.
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835322
Human InsR, IGF1R, and IRR receptor tyrosine kinases (RTK) of the insulin receptor subfamily play an important role in signaling pathways for a wide range of physiological processes and are...
3.
Urban A, Pavlov K, Kamynina A, Okhrimenko I, Arseniev A, Bocharov E
Molecules
. 2021 Jun;
26(10).
PMID: 34068293
Alzheimer's disease is the most common type of neurodegenerative disease in the world. Genetic evidence strongly suggests that aberrant generation, aggregation, and/or clearance of neurotoxic amyloid-β peptides () triggers the...
4.
Bocharov E, Nadezhdin K, Urban A, Volynsky P, Pavlov K, Efremov R, et al.
ACS Chem Biol
. 2019 Jun;
14(7):1573-1582.
PMID: 31180641
Alzheimer's disease is an age-related pathology associated with accumulation of amyloid-β peptides, products of enzymatic cleavage of amyloid-β precursor protein (APP) by secretases. Several familial mutations causing early onset of...
5.
Membrane Elastic Deformations Modulate Gramicidin A Transbilayer Dimerization and Lateral Clustering
Kondrashov O, Galimzyanov T, Pavlov K, Kotova E, Antonenko Y, Akimov S
Biophys J
. 2018 Jul;
115(3):478-493.
PMID: 30049405
Gramicidin A (gA) is a short β-helical peptide known to form conducting channels in lipid membranes because of transbilayer dimerization. The gA conducting dimer, being shorter than the lipid bilayer...
6.
Molotkovsky R, Alexandrova V, Galimzyanov T, Jimenez-Munguia I, Pavlov K, Batishchev O, et al.
Int J Mol Sci
. 2018 May;
19(5).
PMID: 29772704
Sphingomyelin- and cholesterol- enriched membrane domains, commonly referred to as "rafts" play a crucial role in a large number of intra- and intercellular processes. Recent experiments suggest that not only...
7.
Akimov S, Polynkin M, Jimenez-Munguia I, Pavlov K, Batishchev O
Int J Mol Sci
. 2018 May;
19(5).
PMID: 29751591
Membrane fusion mediates multiple vital processes in cell life. Specialized proteins mediate the fusion process, and a substantial part of their energy is used for topological rearrangement of the membrane...
8.
Bocharov E, Lesovoy D, Bocharova O, Urban A, Pavlov K, Volynsky P, et al.
Biochim Biophys Acta Gen Subj
. 2018 Mar;
1862(6):1410-1420.
PMID: 29571748
Background: Prior studies of the human growth hormone receptor (GHR) revealed a distinct role of spatial rearrangements of its dimeric transmembrane domain in signal transduction across membrane. Detailed structural information...
9.
Molotkovsky R, Galimzyanov T, Jimenez-Munguia I, Pavlov K, Batishchev O, Akimov S
Int J Mol Sci
. 2017 Dec;
18(12).
PMID: 29207481
Fusion of cellular membranes during normal biological processes, including proliferation, or synaptic transmission, is mediated and controlled by sophisticated protein machinery ensuring the preservation of the vital barrier function of...
10.
Akimov S, Volynsky P, Galimzyanov T, Kuzmin P, Pavlov K, Batishchev O
Sci Rep
. 2017 Oct;
7(1):12509.
PMID: 28970526
Lipid membranes are extremely stable envelopes allowing cells to survive in various environments and to maintain desired internal composition. Membrane permeation through formation of transversal pores requires substantial external stress....