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» Authors » Konstantin V Pavlov

Konstantin V Pavlov

Explore the profile of Konstantin V Pavlov including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 20
Citations 383
Followers 0
Related Specialties
Biochemistry
Chemistry
Biophysics
Top 10 Co-Authors
Eduard V Bocharov
Alexander S Arseniev
Sergey A Akimov
Pavel E Volynsky
Roman G Efremov
Olga V Bocharova
Oleg V Batishchev
Timur R Galimzyanov
Anatoly S Urban
Irene Jimenez-Munguia
Published In
Int J Mol Sci
J Biol Chem
Biochim Biophys Acta Biomembr
Sci Rep
Top Curr Chem
Affiliations
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Recent Articles
11.
Pore formation in lipid membrane I: Continuous reversible trajectory from intact bilayer through hydrophobic defect to transversal pore
Akimov S, Volynsky P, Galimzyanov T, Kuzmin P, Pavlov K, Batishchev O
Sci Rep . 2017 Sep; 7(1):12152. PMID: 28939906
Lipid membranes serve as effective barriers allowing cells to maintain internal composition differing from that of extracellular medium. Membrane permeation, both natural and artificial, can take place via appearance of...
12.
The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane Environment
Bocharov E, Bragin P, Pavlov K, Bocharova O, Mineev K, Polyansky A, et al.
Biochemistry . 2017 Mar; 56(12):1697-1705. PMID: 28291355
The epidermal growth factor receptor (EGFR) family is an important class of receptor tyrosine kinases, mediating a variety of cellular responses in normal biological processes and in pathological states of...
13.
Conformational transitions and interactions underlying the function of membrane embedded receptor protein kinases
Bocharov E, V Sharonov G, Bocharova O, Pavlov K
Biochim Biophys Acta Biomembr . 2017 Jan; 1859(9 Pt A):1417-1429. PMID: 28131853
Among membrane receptors, the single-span receptor protein kinases occupy a broad but specific functional niche determined by distinctive features of the underlying transmembrane signaling mechanisms that are briefly overviewed on...
14.
Helix-helix interactions in membrane domains of bitopic proteins: Specificity and role of lipid environment
Bocharov E, Mineev K, Pavlov K, Akimov S, Kuznetsov A, Efremov R, et al.
Biochim Biophys Acta Biomembr . 2016 Nov; 1859(4):561-576. PMID: 27884807
Interaction between transmembrane helices often determines biological activity of membrane proteins. Bitopic proteins, a broad subclass of membrane proteins, form dimers containing two membrane-spanning helices. Some aspects of their structure-function...
15.
Alternative packing of EGFR transmembrane domain suggests that protein-lipid interactions underlie signal conduction across membrane
Bocharov E, Lesovoy D, Pavlov K, Pustovalova Y, Bocharova O, Arseniev A
Biochim Biophys Acta . 2016 Feb; 1858(6):1254-61. PMID: 26903218
The human epidermal growth factor receptor (EGFR) of HER/ErbB receptor tyrosine kinase family mediates a broad spectrum of cellular responses transducing biochemical signals via lateral dimerization in plasma membrane, while...
16.
Metabolic Precursor of Cholesterol Causes Formation of Chained Aggregates of Liquid-Ordered Domains
Staneva G, Osipenko D, Galimzyanov T, Pavlov K, Akimov S
Langmuir . 2016 Jan; 32(6):1591-600. PMID: 26783730
7-Dehydrocholesterol, an immediate metabolic predecessor of cholesterol, can accumulate in tissues due to some metabolic abnormalities, causing an array of symptoms known as Smith-Lemli-Opitz syndrome. Enrichment of cellular membranes with...
17.
Modulation of the Bioactive Conformation of Transforming Growth Factor β: Possible Implications of Cation Binding for Biological Function
Bocharov E, Pavlov K, Blommers M, Arvinte T, Arseniev A
Top Curr Chem . 2013 Apr; 273:155-81. PMID: 23605462
In any organism, very precisely adjusted interaction and exchange of information between cellsis continuously required. These cooperative interactions involve numerous cytokines, acting throughcorresponding sets of cell-surface receptors. The transforming growth...
18.
Structure elucidation of dimeric transmembrane domains of bitopic proteins
Bocharov E, Volynsky P, Pavlov K, Efremov R, Arseniev A
Cell Adh Migr . 2010 Apr; 4(2):284-98. PMID: 20421711
The interaction between transmembrane helices is of great interest because it directly determines biological activity of a membrane protein. Either destroying or enhancing such interactions can result in many diseases...
19.
Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger
Bocharov E, Pustovalova Y, Pavlov K, Volynsky P, Goncharuk M, Ermolyuk Y, et al.
J Biol Chem . 2007 Apr; 282(22):16256-66. PMID: 17412696
BNip3 is a prominent representative of apoptotic Bcl-2 proteins with rather unique properties initiating an atypical programmed cell death pathway resembling both necrosis and apoptosis. Many Bcl-2 family proteins modulate...
20.
Two germatranes with bulky substituents
Korlyukov A, Komissarov E, Alekseev N, Pavlov K, Krivolapova O, Lachtin V
Acta Crystallogr C . 2006 Jul; 62(Pt 7):m303-5. PMID: 16823198
In 1-adamantyl-2,8,9-trioxa-5-aza-1-germabicyclo[3.3.3]undecane or 1-adamantylgermatrane, [Ge(C(10)H(15))(C(6)H(12)NO(3))], (I), and (2,8,9-trioxa-5-aza-1-germabicyclo[3.3.3]undecan-1-yl)methyl N-cyclohexylcarbamate or [(germatran-1-yl)methyl] N-cyclohexylcarbamate, [Ge(C(6)H(12)NO(3))(C(8)H(14)NO(2))], (II), the Ge atoms are characterized by trigonal-bypiramidal configurations. The Ge...N distances [2.266 (3) and 2.206 (3)...