Konstantin V Kudryavtsev
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Explore the profile of Konstantin V Kudryavtsev including associated specialties, affiliations and a list of published articles.
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25
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Recent Articles
1.
Bozhkova S, Gordina E, Labutin D, Netylko G, Ivantcova P, Kudryavtsev K
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39595995
Targeting virulence determinants is a promising approach to controlling infections in the face of the global spread of antibiotic resistance. -induced peritonitis often occurs in dialysis, implant and trauma patients....
2.
Shulga D, Kudryavtsev K
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39457061
Sortase A (SrtA) of has long been shown to be a relevant molecular target for antibacterial development. Moreover, the designed SrtA inhibitors act via the antivirulence mechanism, potentially causing less...
3.
Ivantcova P, Kirsanova A, Polshakov V, Lyssenko K, Kudryavtsev K
Org Lett
. 2023 Oct;
25(41):7573-7577.
PMID: 37801732
5-Arylpyrrolidine-2-carboxylates with an -halogen substituent at 5-aryl and an electron-withdrawing group at the C position of the pyrrolidine ring were transformed into 1-benzo[]azepine-2-carboxylates under Cu(I) promotion and microwave activation. Reaction...
4.
Bozhkova S, Gordina E, Labutin D, Kudryavtsev K
Antibiotics (Basel)
. 2022 Dec;
11(12).
PMID: 36551492
Prevention of bacterial adhesion is one of the most important antivirulence strategies for meeting the global challenge posed by antimicrobial resistance. We aimed to investigate the influence of a peptidic...
5.
Shulga D, Kudryavtsev K
Molecules
. 2022 Dec;
27(23).
PMID: 36500275
Sortase A (SrtA) of is a well-defined molecular target to combat the virulence of these clinically important bacteria. However up to now no efficient drugs or even clinical candidates are...
6.
Shulga D, Kudryavtsev K
Molecules
. 2021 Dec;
26(24).
PMID: 34946760
Sortase A (SrtA) of has been identified as a promising target to a new type of antivirulent drugs, and therefore, the design of lead molecules with a low nanomolar range...
7.
Mantsyzov A, Sokolov M, Ivantcova P, Brase S, Polshakov V, Kudryavtsev K
J Org Chem
. 2020 Jun;
85(14):8865-8871.
PMID: 32526142
All possible variants of β-proline functionalized tripeptides consisting of homo/hetero chiral monomeric all- 5-arylpyrrolidine-2,4-dicarboxylate units were synthesized for the first time by a nonpeptidic coupling method based on 1,3-dipolar cycloaddition...
8.
Ivantcova P, Kudryavtsev K
Chirality
. 2020 Mar;
32(6):833-841.
PMID: 32168390
4-l-menthyloxycarbonyl 5-aryl prolinates were studied as organocatalysts of a novel three-component reaction of cyclohexanone, benzoic acid, and β-nitrostyrene. The presence of ortho-halogen atom in 5-aryl fragment of the catalyst is...
9.
Ivantcova P, Sokolov M, Kudryavtsev K, Churakov A
Acta Crystallogr E Crystallogr Commun
. 2019 May;
75(Pt 5):537-539.
PMID: 31110780
The title compound, CHNO, represents a chiral β-proline dipeptide. Corresponding stereogenic centres of constituting pyrrolidine units have opposite absolute configurations. The central amide fragment is planar within 0.1 Å and...
10.
Mantsyzov A, Savelyev O, Ivantcova P, Brase S, Kudryavtsev K, Polshakov V
Front Chem
. 2018 Apr;
6:91.
PMID: 29644215
Synthetic β-peptides are potential functional mimetics of native α-proteins. A recently developed, novel, synthetic approach provides an effective route to the broad group of β-proline oligomers with alternating patterns of...