Kong-Peng Lam
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Explore the profile of Kong-Peng Lam including associated specialties, affiliations and a list of published articles.
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91
Citations
2775
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Recent Articles
1.
Neo S, Shuen T, Khare S, Chong J, Lau M, Shirgaonkar N, et al.
JCI Insight
. 2025 Feb;
PMID: 39998891
The functional plasticity of tumor-infiltrating B (TIL-B) cells spans from anti-tumor responses to non-canonical immune suppression. Yet, how tumor microenvironment (TME) influences TIL-B development is still underappreciated. Our current study...
2.
Tan I, Chothani S, Lim H, Lam K
Sci Rep
. 2025 Jan;
15(1):3360.
PMID: 39870744
The tumor suppressor LKB1/STK11 plays important roles in regulating cellular metabolism and stress responses and its mutations are associated with various cancers. We recently identified a novel exon 1b within...
3.
Zhang M, Loh H, Goh Fang S, Yang Y, Lam K, Xu S
Antibodies (Basel)
. 2024 Dec;
13(4).
PMID: 39727480
Background: B-cell maturation antigen (BCMA)-targeted T cell-redirecting immunotherapies, including Chimeric Antigen Receptor (CAR) T-cell therapy and T-cell engagers have demonstrated remarkable success in treating relapsed/refractory (RR) multiple myeloma (MM), a...
4.
Tan C, Zhu F, Chia W, Young B, Yeoh A, Althaus T, et al.
Hlife
. 2024 Jul;
1(1):26-34.
PMID: 38994526
Multiple Omicron sub-lineages have emerged, with Omicron XBB and XBB.1.5 subvariants becoming the dominant variants globally at the time of this study. The key feature of new variants is their...
5.
Neo S, Oliveira M, Tong L, Chen Y, Chen Z, Cismas S, et al.
J Exp Clin Cancer Res
. 2024 Jan;
43(1):13.
PMID: 38191418
Background: Inflammation in the eye is often associated with aggravated ocular diseases such as uveal melanoma (UM). Poor prognosis of UM is generally associated with high potential of metastatic liver...
6.
Loh J, Teo J, Kannan S, Verma C, Andiappan A, Lim H, et al.
Sci Signal
. 2023 Oct;
16(809):eadg5171.
PMID: 37906628
The scaffolding protein CARD11 is a critical mediator of antigen receptor signaling in lymphocytes. Hypomorphic (partial loss-of-function) mutations in CARD11 are associated with the development of severe atopic dermatitis, in...
7.
Zhang M, Lam K, Xu S
Front Immunol
. 2023 Aug;
14:1207276.
PMID: 37638058
Natural Killer (NK) cells are a type of innate lymphoid cells that play a crucial role in immunity by killing virally infected or tumor cells and secreting cytokines and chemokines....
8.
Loh J, Teo J, Kannan S, Verma C, Lim H, Lam K
Pharmaceutics
. 2023 Jul;
15(7).
PMID: 37513967
Invasive fungal disease is an emerging and serious public health threat globally. The expanding population of susceptible individuals, together with the rapid emergence of multidrug-resistant fungi pathogens, call for the...
9.
Tan I, Xu S, Huo J, Huang Y, Lim H, Lam K
J Biol Chem
. 2023 Jun;
299(7):104906.
PMID: 37302555
The tumor suppressor Liver Kinase B1 (LKB1) is a multifunctional serine/threonine protein kinase that regulates cell metabolism, polarity, and growth and is associated with Peutz-Jeghers Syndrome and cancer predisposition. The...
10.
Teo K, Zhang S, Loh J, Lai R, Hey H, Lam K, et al.
Pharmaceutics
. 2023 May;
15(5).
PMID: 37242732
Mesenchymal stem/stromal cell (MSC) exosomes have been shown to alleviate immune dysfunction and inflammation in preclinical animal models. This therapeutic effect is attributed, in part, to their ability to promote...