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Klaus I Matthaei

Explore the profile of Klaus I Matthaei including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 1909
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Recent Articles
11.
Howitt L, Chaston D, Sandow S, Matthaei K, Edwards F, Hill C
J Physiol . 2013 Feb; 591(8):2157-73. PMID: 23440962
Regulation of blood flow in microcirculatory networks depends on spread of local vasodilatation to encompass upstream arteries; a process mediated by endothelial conduction of hyperpolarization. Given that endothelial coupling is...
12.
Tendongfor N, Wanji S, Ngwa J, Esum M, Specht S, Enyong P, et al.
Parasit Vectors . 2012 Feb; 5:43. PMID: 22348321
Background: Immunological mechanisms involved in the survival and development of human filarial species in the vertebrate host are poorly known due to the lack of suitable experimental models. In order...
13.
Barrientos G, Feng W, Truong K, Matthaei K, Yang T, Allen P, et al.
J Biol Chem . 2011 Dec; 287(4):2863-76. PMID: 22139840
Malignant hyperthermia susceptibility (MHS) is primarily conferred by mutations within ryanodine receptor type 1 (RYR1). Here we address how the MHS mutation T4826I within the S4-S5 linker influences excitation-contraction coupling...
14.
Yuen B, Boncompagni S, Feng W, Yang T, Lopez J, Matthaei K, et al.
FASEB J . 2011 Dec; 26(3):1311-22. PMID: 22131268
Mutation T4825I in the type 1 ryanodine receptor (RYR1(T4825I/+)) confers human malignant hyperthermia susceptibility (MHS). We report a knock-in mouse line that expresses the isogenetic mutation T4826I. Heterozygous RYR1(T4826I/+) (Het)...
15.
Blackburn A, Coggan M, Shield A, Cappello J, Theodoratos A, Murray T, et al.
Lab Invest . 2011 Aug; 91(11):1572-83. PMID: 21826057
Glutathione transferase kappa (GSTK1-1) is a highly conserved, mitochondrial enzyme potentially involved in redox reactions. GSTK1-1-deficient mice were generated to further study the enzyme's biological role. Reduced and total glutathione...
16.
Thomsen N, Chappell A, Ali R, Jones T, Adams D, Matthaei K, et al.
Genesis . 2011 Jul; 49(8):681-8. PMID: 21786402
The gelsolin related actin binding protein, Flii, is able to regulate wound healing; mice with decreased Flii expression show improved wound healing whereas mice with elevated Flii expression exhibit impaired...
17.
Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, et al.
J Immunol . 2011 Apr; 186(10):5938-48. PMID: 21482736
Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in infants. In human infants, plasmacytoid dendritic cells (pDC) are recruited to the nasal compartment during...
18.
Matthaei K, Frese M, Hill C
Proc Natl Acad Sci U S A . 2011 Mar; 108(12):E43. PMID: 21402945
No abstract available.
19.
Wu D, Ahrens R, Osterfeld H, Noah T, Groschwitz K, Foster P, et al.
J Biol Chem . 2011 Feb; 286(15):13357-69. PMID: 21303908
Interleukin-13 (IL-13) has been linked to the pathogenesis of inflammatory diseases of the gastrointestinal tract. It is postulated that IL-13 drives inflammatory lesions through the modulation of both hematopoietic and...
20.
Sutherland D, Ranasinghe C, Regner M, Phipps S, Matthaei K, Day S, et al.
Immunol Cell Biol . 2010 Dec; 89(6):706-15. PMID: 21173782
Using Toll-like receptor (TLR) and MyD88 gene knock-out (GKO) mice the effect of TLRs and MyD88 on virus replication, interferon (IFN)-β production, natural killer (NK) cell and CD8T cell responses...