Simon Phipps
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Explore the profile of Simon Phipps including associated specialties, affiliations and a list of published articles.
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112
Citations
4057
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Recent Articles
1.
Sebina I, Bidgood C, Stalley F, Hartel G, Stark T, Callaway L, et al.
Sci Rep
. 2024 Dec;
14(1):30027.
PMID: 39627409
Mechanisms linking pre-pregnancy obesity to increased preterm birth risk are unclear. Here, we examined the impact of pre-pregnancy obesity on metabolites, Fms-related tyrosine kinase 3 ligand (Flt3L), and proinflammatory cytokine...
2.
Ullah M, Rittchen S, Li J, Curren B, Namubiru P, Ahmed T, et al.
Nat Commun
. 2024 Nov;
15(1):10253.
PMID: 39592603
Prostaglandin D2 (PGD2) signals via the DP1 and DP2 receptors. In Phase II trials, DP2 antagonism decreased airway inflammation and airway smooth muscle (ASM) area in moderate-to-severe asthma patients. However,...
3.
Curren B, Ahmed T, Rashid R, Sebina I, Sikder M, Howard D, et al.
Cell Rep
. 2024 Nov;
43(11):114974.
PMID: 39535919
A poor maternal diet during pregnancy predisposes the infant to severe lower respiratory tract infections (sLRIs), which, in turn, increases childhood asthma risk; however, the underlying mechanisms remain poorly understood....
4.
Sebina I, Ngo S, Rashid R, Alorro M, Namubiru P, Howard D, et al.
Immunology
. 2024 Apr;
172(3):500-515.
PMID: 38584001
Lifestyle factors like poor maternal diet or antibiotic exposure disrupt early life microbiome assembly in infants, increasing the risk of severe lower respiratory infections (sLRI). Our prior studies in mice...
5.
Ibrahim J, Dao N, Haque S, Phipps S, Whittaker M, Kaminskas L
J Pharm Sci
. 2024 Mar;
113(5):1395-1400.
PMID: 38460572
Liposomes are being developed as inhalable drug delivery systems, but concerns remain about their impact on the lungs. To better understand the impact of liposomes and their physicochemical properties on...
6.
Moniruzzaman M, Rahman M, Wang R, Wong K, Chen A, Mueller A, et al.
J Exp Med
. 2023 Sep;
220(11).
PMID: 37695525
Major histocompatibility complex (MHC) II is dynamically expressed on mucosal epithelial cells and is induced in response to inflammation and parasitic infections, upon exposure to microbiota, and is increased in...
7.
Curren B, Ahmed T, Howard D, Ullah M, Sebina I, Rashid R, et al.
Mucosal Immunol
. 2023 Jul;
16(5):671-684.
PMID: 37506849
Rhinovirus-induced neutrophil extracellular traps (NETs) contribute to acute asthma exacerbations; however, the molecular factors that trigger NETosis in this context remain ill-defined. Here, we sought to implicate a role for...
8.
Moore J, Navarro S, McCarthy K, Rashid R, Phipps S, Amoako A, et al.
Acta Obstet Gynecol Scand
. 2023 Apr;
102(7):811-820.
PMID: 37067195
With increasing rates of cesarean section worldwide and international guidelines advising pre-incision antibiotics, neonatal exposure to pre-birth antibiotics is higher than ever before. Emerging evidence has raised concern regarding the...
9.
Reuben R, Hammer S, Johnson O, Good D, Palacio-Torralba J, Candito A, et al.
Proc Inst Mech Eng H
. 2023 Apr;
237(5):571-584.
PMID: 37062899
A calibrated palpation sensor has been developed for making instrumented Digital Rectal Examinations (iDREs) with a view to assessing patients for prostate cancer. The instrument measures the dynamic stiffness of...
10.
Sikder M, Rashid R, Ahmed T, Sebina I, Howard D, Ullah M, et al.
Immunity
. 2023 Apr;
56(5):1098-1114.e10.
PMID: 37003256
Poor maternal diet during pregnancy is a risk factor for severe lower respiratory infections (sLRIs) in the offspring, but the underlying mechanisms remain elusive. Here, we demonstrate that in mice...