Kirsten A Cottrill
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Explore the profile of Kirsten A Cottrill including associated specialties, affiliations and a list of published articles.
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15
Citations
82
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Recent Articles
1.
Cottrill K, Miles C, Krajewski L, Cunningham B, Bragg W, Boise N, et al.
Harmful Algae
. 2024 Nov;
139:102739.
PMID: 39567074
Background: Microcystins are an emergent public health problem. These toxins are secondary metabolites of harmful cyanobacterial blooms, with blooms becoming more prevalent with eutrophication of water. Exposure to microcystins can...
2.
Vazquez Cegla A, Jones K, Cui G, Cottrill K, Koval M, McCarty N
Sci Rep
. 2024 Oct;
14(1):25095.
PMID: 39443580
Cystic fibrosis related diabetes (CFRD), the main co-morbidity in cystic fibrosis (CF), is associated with higher rates of lung function decline. We hypothesize that airway epithelial barrier function is impaired...
3.
Cottrill K, Chandler J, Kobara S, Stephenson S, Mohammad A, Tidwell M, et al.
J Allergy Clin Immunol Glob
. 2023 Aug;
2(3).
PMID: 37609569
Background: Asthma exacerbations are highly prevalent in children, but only a few studies have examined the biologic mechanisms underlying exacerbations in this population. Objective: High-resolution metabolomics analyses were performed to...
4.
Kim S, Shapiro J, Cottrill K, Collins G, Shanthikumar S, Rao P, et al.
Free Radic Biol Med
. 2023 Jun;
206:180-190.
PMID: 37356776
Myeloperoxidase (MPO) is released by neutrophils in inflamed tissues. MPO oxidizes chloride, bromide, and thiocyanate to produce hypochlorous acid (HOCl), hypobromous acid (HOBr), and hypothiocyanous acid (HOSCN), respectively. These oxidants...
5.
Geitgey D, Lee M, Cottrill K, Jaffe M, Pilcher W, Bhasin S, et al.
J Natl Cancer Inst Monogr
. 2023 May;
2023(61):12-29.
PMID: 37139973
The obesity pandemic currently affects more than 70 million Americans and more than 650 million individuals worldwide. In addition to increasing susceptibility to pathogenic infections (eg, SARS-CoV-2), obesity promotes the...
6.
Cottrill K, Rad M, Ripple M, Stephenson S, Mohammad A, Tidwell M, et al.
Sci Rep
. 2023 Mar;
13(1):3521.
PMID: 36864187
Children with life-threatening asthma exacerbations who are admitted to a pediatric intensive care unit (PICU) are a heterogeneous group with poorly studied inflammatory features. We hypothesized that distinct clusters of...
7.
Fitzpatrick A, Grunwell J, Cottrill K, Mutic A, Mauger D
J Allergy Clin Immunol Pract
. 2023 Feb;
11(5):1485-1493.e8.
PMID: 36738927
Background: Although clinical features of type 2 inflammation have been associated with poorer longitudinal outcomes in preschool children with recurrent wheezing, it remains difficult to predict which children are at...
8.
Cottrill K, Stephenson S, Mohammad A, Kim S, McCarty N, Kamaleswaran R, et al.
J Allergy Clin Immunol
. 2022 Sep;
151(1):118-127.e10.
PMID: 36096204
Background: The asthma of some children remains poorly controlled, with recurrent exacerbations despite treatment with inhaled corticosteroids. Aside from prior exacerbations, there are currently no reliable predictors of exacerbation-prone asthma...
9.
Cottrill K, Giacalone V, Margaroli C, Bridges R, Koval M, Tirouvanziam R, et al.
Physiol Rep
. 2021 Sep;
9(17):e15023.
PMID: 34514718
Loss of function of the cystic fibrosis transmembrane conductance regulator (CFTR) causes cystic fibrosis (CF). In the lungs, this manifests as immune cell infiltration and bacterial infections, leading to tissue...
10.
Cottrill K, Peterson R, Lewallen C, Koval M, Bridges R, McCarty N
Physiol Rep
. 2021 Aug;
9(15):e14928.
PMID: 34382377
The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel whose dysfunction causes cystic fibrosis (CF). The loss of CFTR function in pulmonary epithelial cells causes surface dehydration, mucus...