Kirill Alexandrov
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Explore the profile of Kirill Alexandrov including associated specialties, affiliations and a list of published articles.
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142
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2628
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Recent Articles
1.
Guo Z, Smutok O, Ronacher C, Aguiar Rocha R, Walden P, Mureev S, et al.
Angew Chem Int Ed Engl
. 2025 Jan;
64(9):e202411584.
PMID: 39856018
Lanthanides, which are part of the rare earth elements group have numerous applications in electronics, medicine and energy storage. However, our ability to extract them is not meeting the rapidly...
2.
Johnston W, Palma J, Alexandrov K
J Vis Exp
. 2024 Nov;
(213).
PMID: 39584703
This protocol outlines the production and optimization of a eukaryotic Cell-Free Protein Expression System (CFPS) derived from the unicellular flagellate Leishmania tarentolae, referred to as Leishmania Translational Extract or LTE....
3.
Rocha R, Alexandrov K, Scott C
Microb Biotechnol
. 2024 Jun;
17(6):e14503.
PMID: 38829373
Rare earth elements (REEs) are critical for our modern lifestyles and the transition to a low-carbon economy. Recent advances in our understanding of the role of REEs in biology, particularly...
4.
Cui Z, Ayva C, Liew Y, Guo Z, Mutschler R, Dreier B, et al.
ACS Sens
. 2024 May;
9(6):2846-2857.
PMID: 38807313
Despite the significant potential of protein biosensors, their construction remains a trial-and-error process. The most obvious approach for addressing this is to utilize modular biosensor architectures where specificity-conferring modalities can...
5.
Alfaro-Palma J, Johnston W, Behrendorff J, Cui Z, Moradi S, Alexandrov K
ACS Synth Biol
. 2024 Jan;
13(2):449-456.
PMID: 38268082
Eukaryotic cell-free protein expression systems enable rapid production of recombinant multidomain proteins in their functional form. A cell-free system based on the rapidly growing protozoan (LTE) has been extensively used...
6.
Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, et al.
Elife
. 2023 Aug;
12.
PMID: 37551662
No abstract available.
7.
Development of epistatic YES and AND protein logic gates and their assembly into signalling cascades
Guo Z, Smutok O, Ayva C, Walden P, Parker J, Whitfield J, et al.
Nat Nanotechnol
. 2023 Jul;
18(11):1327-1334.
PMID: 37500780
The construction and assembly of artificial allosteric protein switches into information and energy processing networks connected to both biological and non-biological systems is a central goal of synthetic biology and...
8.
Moradi S, Wu Y, Walden P, Cui Z, Johnston W, Petrov D, et al.
ACS Omega
. 2023 Jul;
8(28):25009-25019.
PMID: 37483225
The emergence of viral threats such as Ebola, ZIKA, and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requires a rapid and efficient approach for elucidating mechanisms of pathogenesis and development of...
9.
Das Gupta K, Ramnath D, von Pein J, Curson J, Wang Y, Abrol R, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(4):e2212813120.
PMID: 36649417
The immune system must be able to respond to a myriad of different threats, each requiring a distinct type of response. Here, we demonstrate that the cytoplasmic lysine deacetylase HDAC7...
10.
Wells P, Smutok O, Guo Z, Alexandrov K, Katz E
Talanta
. 2023 Jan;
255:124215.
PMID: 36603441
Protein biosensors hold a promise to transform the way we collect physiological data by enabling quantification of biomarkers outside of specialized laboratory environment. However, achieving high specificity and sensitivity in...