Herbert Waldmann
Overview
Explore the profile of Herbert Waldmann including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
439
Citations
9611
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Binici A, Hennes E, Koska S, Alexander Niemann J, Reich A, Pfaff C, et al.
Chemistry
. 2025 Feb;
:e202404006.
PMID: 39932696
The tumor microenvironment (TME) is a pro-cancerous niche harboring immunosuppressive factors that are secreted by cancer cells and the surrounding cancer-supportive tissue, such as kynurenine, prostaglandin E2 and transforming growth...
2.
Bauer L, Ward J, Diaz-Saez L, Sundstrom Y, Tolvanen T, Alarcon Barrera J, et al.
Angew Chem Int Ed Engl
. 2024 Dec;
64(7):e202420149.
PMID: 39740997
Choline kinase alpha (CHKA) is a central mediator of cell metabolism linked to cancer and immune regulation. Cellular and clinical evaluation of CHKA has been hampered by challenges in the...
3.
Alkhalaf L, Arrowsmith C, Balskus E, Bergamini G, Bhandari R, Chang C, et al.
Nat Chem Biol
. 2024 Dec;
21(1):6-15.
PMID: 39719500
No abstract available.
4.
Heinzke A, Zdrazil B, Leeson P, Young R, Pahl A, Waldmann H, et al.
Sci Data
. 2024 Oct;
11(1):1160.
PMID: 39433759
Providing a better understanding of what makes a compound a successful drug candidate is crucial for reducing the high attrition rates in drug discovery. Analyses of the differences between active...
5.
Tandon A, Santura A, Waldmann H, Pahl A, Czodrowski P
RSC Med Chem
. 2024 Aug;
15(8):2677-2691.
PMID: 39149097
Lysosomotropism is a phenomenon of diverse pharmaceutical interests because it is a property of compounds with diverse chemical structures and primary targets. While it is primarily reported to be caused...
6.
Pahl A, Grygorenko O, Kondratov I, Waldmann H
RSC Med Chem
. 2024 Aug;
15(8):2709-2717.
PMID: 39149091
Pseudo-natural products (PNPs) combine fragments derived from NPs in ways that are not found in nature, and may lead to the discovery of novel chemotypes for unexpected targets or the...
7.
Hennes E, Lucas B, Scholes N, Cheng X, Scott D, Bischoff M, et al.
bioRxiv
. 2024 Jul;
PMID: 39026748
Targeted protein degradation (TPD) modulates protein function beyond inhibition of enzyme activity or protein-protein interactions. Most degrader drugs function by directly mediating proximity between a neosubstrate and hijacked E3 ligase....
8.
Rezaei Adariani S, Agne D, Koska S, Burhop A, Seitz C, Warmers J, et al.
J Med Chem
. 2024 Jul;
67(15):13252-13270.
PMID: 39018123
Mitochondria are cellular powerhouses and are crucial for cell function. However, they are vulnerable to internal and external perturbagens that may impair mitochondrial function and eventually lead to cell death....
9.
Heinzke A, Pahl A, Zdrazil B, Leach A, Waldmann H, Young R, et al.
J Med Chem
. 2024 Jul;
67(13):11226-11241.
PMID: 38949112
Published compounds from ChEMBL version 32 are used to seek evidence for the occurrence of "natural selection" in drug discovery. Three measures of natural product (NP) character were applied, to...
10.
Cigler M, Imrichova H, Frommelt F, Caramelle L, Depta L, Rukavina A, et al.
Nat Chem Biol
. 2024 Jun;
21(2):193-202.
PMID: 38907113
Metabolic alterations in cancer precipitate in associated dependencies that can be therapeutically exploited. To meet this goal, natural product-inspired small molecules can provide a resource of invaluable chemotypes. Here, we...