Kim Nasmyth
Overview
Explore the profile of Kim Nasmyth including associated specialties, affiliations and a list of published articles.
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100
Citations
9682
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Recent Articles
1.
Nasmyth K
Nat Rev Genet
. 2022 May;
23(7):447-452.
PMID: 35595848
July 2022 will see the bicentenary of the birth of Gregor Mendel, often hailed as the 'father of modern genetics'. To mark the occasion, I retrace Mendel's origins, revisit his...
2.
Houlard M, Cutts E, Shamim M, Godwin J, Weisz D, Presser Aiden A, et al.
Elife
. 2021 Dec;
10.
PMID: 34850681
Dramatic change in chromosomal DNA morphology between interphase and mitosis is a defining features of the eukaryotic cell cycle. Two types of enzymes, namely cohesin and condensin confer the topology...
3.
Ogushi S, Rattani A, Godwin J, Metson J, Schermelleh L, Nasmyth K
Dev Cell
. 2021 Nov;
56(22):3100-3114.e4.
PMID: 34758289
Protection of peri-centromeric (periCEN) REC8 cohesin from Separase and sister kinetochore (KT) attachment to microtubules emanating from the same spindle pole (co-orientation) ensures that sister chromatids remain associated after meiosis...
4.
Yatskevich S, Rhodes J, Nasmyth K
Annu Rev Genet
. 2019 Oct;
53:445-482.
PMID: 31577909
Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion,...
5.
Chapard C, Jones R, van Oepen T, Scheinost J, Nasmyth K
Mol Cell
. 2019 Jun;
75(2):224-237.e5.
PMID: 31201089
Cohesin entraps sister DNAs within tripartite rings created by pairwise interactions between Smc1, Smc3, and Scc1. Because Smc1/3 ATPase heads can also interact with each other, cohesin rings have the...
6.
Burmann F, Lee B, Than T, Sinn L, OReilly F, Yatskevich S, et al.
Nat Struct Mol Biol
. 2019 Mar;
26(3):227-236.
PMID: 30833788
Structural maintenance of chromosomes (SMC)-kleisin complexes organize chromosomal DNAs in all domains of life, with key roles in chromosome segregation, DNA repair and regulation of gene expression. They function through...
7.
8.
Rhodes J, Mazza D, Nasmyth K, Uphoff S
Elife
. 2017 Sep;
6.
PMID: 28914604
The cohesin complex mediates DNA-DNA interactions both between (sister chromatid cohesion) and within chromosomes (DNA looping). It has been suggested that intra-chromosome loops are generated by extrusion of DNAs through...
9.
Rattani A, Ballesteros Mejia R, Roberts K, B Roig M, Godwin J, Hopkins M, et al.
Curr Biol
. 2017 May;
27(10):1462-1476.e5.
PMID: 28502659
In mammalian females, germ cells remain arrested as primordial follicles. Resumption of meiosis is heralded by germinal vesicle breakdown, condensation of chromosomes, and their eventual alignment on metaphase plates. At...
10.