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Kilian Kleemann

Explore the profile of Kilian Kleemann including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Heneka M, van der Flier W, Jessen F, Hoozemanns J, Thal D, Boche D, et al.
Nat Rev Immunol . 2024 Dec; PMID: 39653749
Increasing evidence points to a pivotal role of immune processes in the pathogenesis of Alzheimer disease, which is the most prevalent neurodegenerative and dementia-causing disease of our time. Multiple lines...
2.
McKinsey G, Santander N, Zhang X, Kleemann K, Tran L, Katewa A, et al.
bioRxiv . 2023 Oct; PMID: 37790363
Microglia diversity emerges from interactions between intrinsic genetic programs and environment-derived signals, but how these processes unfold and interact in the developing brain remains unclear. Here, we show that radial...
3.
Yin Z, Herron S, Silveira S, Kleemann K, Gauthier C, Mallah D, et al.
Nat Neurosci . 2023 Jun; 26(7):1196-1207. PMID: 37291336
Microglia play a critical role in brain homeostasis and disease progression. In neurodegenerative conditions, microglia acquire the neurodegenerative phenotype (MGnD), whose function is poorly understood. MicroRNA-155 (miR-155), enriched in immune...
4.
Brosseron F, Kleemann K, Kolbe C, Santarelli F, Castro-Gomez S, Tacik P, et al.
J Neurochem . 2020 Sep; 157(6):2210-2224. PMID: 32894885
There is growing evidence that promising biomarkers of inflammation in Alzheimer´s disease (AD) and other neurodegenerative diseases correlate strongest to levels of tau or neurofilament, indicating an inflammatory response to...