Frederic Brosseron
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Explore the profile of Frederic Brosseron including associated specialties, affiliations and a list of published articles.
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79
Citations
4765
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Recent Articles
1.
Haag L, Lancini E, Yakupov R, Ziegler G, Yi Y, Lusebrink F, et al.
Brain Commun
. 2025 Feb;
7(1):fcaf031.
PMID: 39926613
Neurotransmitter systems of noradrenaline, dopamine, serotonin and acetylcholine are implicated in cognitive functions such as memory, learning and attention and are known to be altered in neurodegenerative diseases like Alzheimer's...
2.
Schneider L, Freiesleben S, van Breukelen G, Wang X, Brosseron F, Heneka M, et al.
Alzheimers Dement
. 2025 Jan;
21(2):e14545.
PMID: 39868793
Introduction: The beneficial effects of amyloid beta 1-38, or Aβ(1-38), on Alzheimer's disease (AD) progression in humans in vivo remain controversial. We investigated AD patients' cerebrospinal fluid (CSF) Aβ(1-38) and...
3.
Quattrone A, Franzmeier N, Levin J, Petzold G, Spottke A, Brosseron F, et al.
Mov Disord
. 2025 Jan;
PMID: 39797511
Background: The recent Movement Disorders Society (MDS)-progressive supranuclear palsy (PSP) diagnostic criteria conceptualized three clinical diagnostic certainty levels: "suggestive of PSP" for sensitive early diagnosis based on subtle clinical signs,...
4.
Blomeke L, Rehn F, Pils M, Kraemer-Schulien V, Cousin A, Kutzsche J, et al.
Commun Med (Lond)
. 2024 Dec;
4(1):262.
PMID: 39658587
Background: Quantification of Amyloid beta (Aβ) oligomers in plasma enables early diagnosis of Alzheimer's Disease (AD) and improves our understanding of underlying pathologies. However, quantification necessitates an extremely sensitive and...
5.
Heneka M, van der Flier W, Jessen F, Hoozemanns J, Thal D, Boche D, et al.
Nat Rev Immunol
. 2024 Dec;
PMID: 39653749
Increasing evidence points to a pivotal role of immune processes in the pathogenesis of Alzheimer disease, which is the most prevalent neurodegenerative and dementia-causing disease of our time. Multiple lines...
6.
Eberhard J, Henning L, Fulle L, Knopper K, Bohringer J, Graelmann F, et al.
Epilepsia
. 2024 Nov;
66(2):554-568.
PMID: 39607395
Objective: Neuronal cell death and neuroinflammation are characteristic features of epilepsy, but it remains unclear whether neuronal cell death as such is causative for the development of epileptic seizures. To...
7.
Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy E, Bernal J, et al.
Nat Commun
. 2024 Nov;
15(1):9815.
PMID: 39537609
The cognitive reserve (CR) hypothesis posits that individuals can differ in how their brain function is disrupted by pathology associated with aging and neurodegeneration. Here, we test this hypothesis in...
8.
Menze I, Bernal J, Kaya P, Aki C, Pfister M, Geisendorfer J, et al.
Alzheimers Res Ther
. 2024 Nov;
16(1):242.
PMID: 39482759
Background: Perivascular space (PVS) enlargement in ageing and Alzheimer's disease (AD) and the drivers of such a structural change in humans require longitudinal investigation. Elucidating the effects of demographic factors,...
9.
Wang X, Freiesleben S, Schneider L, Preis L, Priller J, Spruth E, et al.
Neurology
. 2024 Sep;
103(8):e209806.
PMID: 39303184
Background And Objectives: CSF biomarkers have immense diagnostic and prognostic potential for Alzheimer disease (AD). However, AD is still diagnosed relatively late in the disease process, sometimes even years after...
10.
Dunnwald M, Krohn F, Sciarra A, Sarkar M, Schneider A, Fliessbach K, et al.
bioRxiv
. 2024 Aug;
PMID: 39091766
Introduction: The Locus Coeruleus (LC) is linked to the development and pathophysiology of neurodegenerative diseases such as Alzheimer's Disease (AD). Magnetic Resonance Imaging based LC features have shown potential to...